Time of maximum cycloplegia after instillation of cyclopentolate 1% in children with brown irises

Sittikorn Laojaroenwanit, Vimontip Layanun, Pokpong Praneeprachachon, Parnchat Pukrushpan Department of Ophthalmology, Faculty of Medicine, Chulalongkorn University, Bangkok, ThailandPurpose: We aimed to 1) determine the time of maximum cycloplegia after instillation of cyclopentolate 1% in children...

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Autores principales:	Laojaroenwanit S, Layanun V, Praneeprachachon P, Pukrushpan P
Formato:	article
Lenguaje:	EN
Publicado:	Dove Medical Press 2016
Materias:	Refraction Cyclopentolate Cycloplegia Brown irises Ophthalmology RE1-994
Acceso en línea:	https://doaj.org/article/aef75e54ec2c4affaf988964f03a4c10
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spelling	oai:doaj.org-article:aef75e54ec2c4affaf988964f03a4c102021-12-02T01:39:07ZTime of maximum cycloplegia after instillation of cyclopentolate 1% in children with brown irises1177-5483https://doaj.org/article/aef75e54ec2c4affaf988964f03a4c102016-05-01T00:00:00Zhttps://www.dovepress.com/time-of-maximum-cycloplegia-after-instillation-of-cyclopentolate-1-in--peer-reviewed-article-OPTHhttps://doaj.org/toc/1177-5483Sittikorn Laojaroenwanit, Vimontip Layanun, Pokpong Praneeprachachon, Parnchat Pukrushpan Department of Ophthalmology, Faculty of Medicine, Chulalongkorn University, Bangkok, ThailandPurpose: We aimed to 1) determine the time of maximum cycloplegia after instillation of cyclopentolate 1% in children with brown irises, 2) evaluate the correlation between the pupillary reaction and time of maximum cycloplegia, and 3) identify any side effects of the medication.Patients and methods: This was a prospective analytical study involving children aged 5 to 14 years who were attending refraction clinic. Cyclopentolate 1% was instilled three times at 10-minute intervals. The spherical equivalent, pupillary reaction, and pupillary diameter were recorded before the first drop and nine times after the last drop at 10-minute intervals. Side effects were assessed. Time of maximum cycloplegia was determined from the time point at which the 95% confidence interval of the differences between the mean spherical equivalent at each point and its final value at 110 minutes was reached and remained within the equivalence limit (±0.25 D).Results: Sixty children were enrolled in this study. Their mean age was 9.8 years (range: 5–14 years). Time of maximum cycloplegia was reached at 30 minutes after the first instillation of cyclopentolate. A poor correlation was observed between the pupillary reaction and the time of maximum cycloplegia (r=−0.07). The mean pupillary diameter at 30 minutes was 3.7±1.3 mm, and further dilation occurred thereafter. No side effects were observed.Conclusion: In most children, maximum cycloplegia was reached 30 minutes after the first instillation of cyclopentolate. The absence of a pupillary reaction should not be used as an indicator of maximum cycloplegia.Keywords: refraction, cyclopentolate, cycloplegia, brown irises, cycloplegic refractionLaojaroenwanit SLayanun VPraneeprachachon PPukrushpan PDove Medical PressarticleRefractionCyclopentolateCycloplegiaBrown irisesOphthalmologyRE1-994ENClinical Ophthalmology, Vol 2016, Iss Issue 1, Pp 897-902 (2016)
institution	DOAJ
collection	DOAJ
language	EN
topic	Refraction Cyclopentolate Cycloplegia Brown irises Ophthalmology RE1-994
spellingShingle	Refraction Cyclopentolate Cycloplegia Brown irises Ophthalmology RE1-994 Laojaroenwanit S Layanun V Praneeprachachon P Pukrushpan P Time of maximum cycloplegia after instillation of cyclopentolate 1% in children with brown irises
description	Sittikorn Laojaroenwanit, Vimontip Layanun, Pokpong Praneeprachachon, Parnchat Pukrushpan Department of Ophthalmology, Faculty of Medicine, Chulalongkorn University, Bangkok, ThailandPurpose: We aimed to 1) determine the time of maximum cycloplegia after instillation of cyclopentolate 1% in children with brown irises, 2) evaluate the correlation between the pupillary reaction and time of maximum cycloplegia, and 3) identify any side effects of the medication.Patients and methods: This was a prospective analytical study involving children aged 5 to 14 years who were attending refraction clinic. Cyclopentolate 1% was instilled three times at 10-minute intervals. The spherical equivalent, pupillary reaction, and pupillary diameter were recorded before the first drop and nine times after the last drop at 10-minute intervals. Side effects were assessed. Time of maximum cycloplegia was determined from the time point at which the 95% confidence interval of the differences between the mean spherical equivalent at each point and its final value at 110 minutes was reached and remained within the equivalence limit (±0.25 D).Results: Sixty children were enrolled in this study. Their mean age was 9.8 years (range: 5–14 years). Time of maximum cycloplegia was reached at 30 minutes after the first instillation of cyclopentolate. A poor correlation was observed between the pupillary reaction and the time of maximum cycloplegia (r=−0.07). The mean pupillary diameter at 30 minutes was 3.7±1.3 mm, and further dilation occurred thereafter. No side effects were observed.Conclusion: In most children, maximum cycloplegia was reached 30 minutes after the first instillation of cyclopentolate. The absence of a pupillary reaction should not be used as an indicator of maximum cycloplegia.Keywords: refraction, cyclopentolate, cycloplegia, brown irises, cycloplegic refraction
format	article
author	Laojaroenwanit S Layanun V Praneeprachachon P Pukrushpan P
author_facet	Laojaroenwanit S Layanun V Praneeprachachon P Pukrushpan P
author_sort	Laojaroenwanit S
title	Time of maximum cycloplegia after instillation of cyclopentolate 1% in children with brown irises
title_short	Time of maximum cycloplegia after instillation of cyclopentolate 1% in children with brown irises
title_full	Time of maximum cycloplegia after instillation of cyclopentolate 1% in children with brown irises
title_fullStr	Time of maximum cycloplegia after instillation of cyclopentolate 1% in children with brown irises
title_full_unstemmed	Time of maximum cycloplegia after instillation of cyclopentolate 1% in children with brown irises
title_sort	time of maximum cycloplegia after instillation of cyclopentolate 1% in children with brown irises
publisher	Dove Medical Press
publishDate	2016
url	https://doaj.org/article/aef75e54ec2c4affaf988964f03a4c10
work_keys_str_mv	AT laojaroenwanits timeofmaximumcycloplegiaafterinstillationofcyclopentolate1inchildrenwithbrownirises AT layanunv timeofmaximumcycloplegiaafterinstillationofcyclopentolate1inchildrenwithbrownirises AT praneeprachachonp timeofmaximumcycloplegiaafterinstillationofcyclopentolate1inchildrenwithbrownirises AT pukrushpanp timeofmaximumcycloplegiaafterinstillationofcyclopentolate1inchildrenwithbrownirises
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Time of maximum cycloplegia after instillation of cyclopentolate 1% in children with brown irises

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