REV-ERBα integrates colon clock with experimental colitis through regulation of NF-κB/NLRP3 axis
REV-ERBα is a nuclear receptor that links the circadian pathways with those of metabolism. Here the authors show REV-ERBα is also involved with linking the circadian system with the inflammatory pathways of an experimental model of colitis through regulation of the NF-κB/NLRP3 axis.
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Nature Portfolio
2018
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oai:doaj.org-article:aeffafb580344074a00dd33fdb500a1c2021-12-02T16:49:18ZREV-ERBα integrates colon clock with experimental colitis through regulation of NF-κB/NLRP3 axis10.1038/s41467-018-06568-52041-1723https://doaj.org/article/aeffafb580344074a00dd33fdb500a1c2018-10-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-06568-5https://doaj.org/toc/2041-1723REV-ERBα is a nuclear receptor that links the circadian pathways with those of metabolism. Here the authors show REV-ERBα is also involved with linking the circadian system with the inflammatory pathways of an experimental model of colitis through regulation of the NF-κB/NLRP3 axis.Shuai WangYanke LinXue YuanFeng LiLianxia GuoBaojian WuNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-12 (2018) |
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Science Q Shuai Wang Yanke Lin Xue Yuan Feng Li Lianxia Guo Baojian Wu REV-ERBα integrates colon clock with experimental colitis through regulation of NF-κB/NLRP3 axis |
description |
REV-ERBα is a nuclear receptor that links the circadian pathways with those of metabolism. Here the authors show REV-ERBα is also involved with linking the circadian system with the inflammatory pathways of an experimental model of colitis through regulation of the NF-κB/NLRP3 axis. |
format |
article |
author |
Shuai Wang Yanke Lin Xue Yuan Feng Li Lianxia Guo Baojian Wu |
author_facet |
Shuai Wang Yanke Lin Xue Yuan Feng Li Lianxia Guo Baojian Wu |
author_sort |
Shuai Wang |
title |
REV-ERBα integrates colon clock with experimental colitis through regulation of NF-κB/NLRP3 axis |
title_short |
REV-ERBα integrates colon clock with experimental colitis through regulation of NF-κB/NLRP3 axis |
title_full |
REV-ERBα integrates colon clock with experimental colitis through regulation of NF-κB/NLRP3 axis |
title_fullStr |
REV-ERBα integrates colon clock with experimental colitis through regulation of NF-κB/NLRP3 axis |
title_full_unstemmed |
REV-ERBα integrates colon clock with experimental colitis through regulation of NF-κB/NLRP3 axis |
title_sort |
rev-erbα integrates colon clock with experimental colitis through regulation of nf-κb/nlrp3 axis |
publisher |
Nature Portfolio |
publishDate |
2018 |
url |
https://doaj.org/article/aeffafb580344074a00dd33fdb500a1c |
work_keys_str_mv |
AT shuaiwang reverbaintegratescolonclockwithexperimentalcolitisthroughregulationofnfkbnlrp3axis AT yankelin reverbaintegratescolonclockwithexperimentalcolitisthroughregulationofnfkbnlrp3axis AT xueyuan reverbaintegratescolonclockwithexperimentalcolitisthroughregulationofnfkbnlrp3axis AT fengli reverbaintegratescolonclockwithexperimentalcolitisthroughregulationofnfkbnlrp3axis AT lianxiaguo reverbaintegratescolonclockwithexperimentalcolitisthroughregulationofnfkbnlrp3axis AT baojianwu reverbaintegratescolonclockwithexperimentalcolitisthroughregulationofnfkbnlrp3axis |
_version_ |
1718383355256373248 |