REV-ERBα integrates colon clock with experimental colitis through regulation of NF-κB/NLRP3 axis

REV-ERBα is a nuclear receptor that links the circadian pathways with those of metabolism. Here the authors show REV-ERBα is also involved with linking the circadian system with the inflammatory pathways of an experimental model of colitis through regulation of the NF-κB/NLRP3 axis.

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Autores principales: Shuai Wang, Yanke Lin, Xue Yuan, Feng Li, Lianxia Guo, Baojian Wu
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2018
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Acceso en línea:https://doaj.org/article/aeffafb580344074a00dd33fdb500a1c
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spelling oai:doaj.org-article:aeffafb580344074a00dd33fdb500a1c2021-12-02T16:49:18ZREV-ERBα integrates colon clock with experimental colitis through regulation of NF-κB/NLRP3 axis10.1038/s41467-018-06568-52041-1723https://doaj.org/article/aeffafb580344074a00dd33fdb500a1c2018-10-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-06568-5https://doaj.org/toc/2041-1723REV-ERBα is a nuclear receptor that links the circadian pathways with those of metabolism. Here the authors show REV-ERBα is also involved with linking the circadian system with the inflammatory pathways of an experimental model of colitis through regulation of the NF-κB/NLRP3 axis.Shuai WangYanke LinXue YuanFeng LiLianxia GuoBaojian WuNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-12 (2018)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Shuai Wang
Yanke Lin
Xue Yuan
Feng Li
Lianxia Guo
Baojian Wu
REV-ERBα integrates colon clock with experimental colitis through regulation of NF-κB/NLRP3 axis
description REV-ERBα is a nuclear receptor that links the circadian pathways with those of metabolism. Here the authors show REV-ERBα is also involved with linking the circadian system with the inflammatory pathways of an experimental model of colitis through regulation of the NF-κB/NLRP3 axis.
format article
author Shuai Wang
Yanke Lin
Xue Yuan
Feng Li
Lianxia Guo
Baojian Wu
author_facet Shuai Wang
Yanke Lin
Xue Yuan
Feng Li
Lianxia Guo
Baojian Wu
author_sort Shuai Wang
title REV-ERBα integrates colon clock with experimental colitis through regulation of NF-κB/NLRP3 axis
title_short REV-ERBα integrates colon clock with experimental colitis through regulation of NF-κB/NLRP3 axis
title_full REV-ERBα integrates colon clock with experimental colitis through regulation of NF-κB/NLRP3 axis
title_fullStr REV-ERBα integrates colon clock with experimental colitis through regulation of NF-κB/NLRP3 axis
title_full_unstemmed REV-ERBα integrates colon clock with experimental colitis through regulation of NF-κB/NLRP3 axis
title_sort rev-erbα integrates colon clock with experimental colitis through regulation of nf-κb/nlrp3 axis
publisher Nature Portfolio
publishDate 2018
url https://doaj.org/article/aeffafb580344074a00dd33fdb500a1c
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AT fengli reverbaintegratescolonclockwithexperimentalcolitisthroughregulationofnfkbnlrp3axis
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