Tracking carrier protein motions with Raman spectroscopy

Acyl carrier proteins (ACPs), a universal and highly conserved carrier of acyl intermediates during fatty acid and polyketide synthesis, are difficult to visualise. Here, the authors developed a facile, Raman spectroscopy-based method to detect ACP-substrate interactions.

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Detalles Bibliográficos
Autores principales: Samuel C. Epstein, Adam R. Huff, Emily S. Winesett, Casey H. Londergan, Louise K. Charkoudian
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2019
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Acceso en línea:https://doaj.org/article/af029210b2084baead366317ac033fb1
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Descripción
Sumario:Acyl carrier proteins (ACPs), a universal and highly conserved carrier of acyl intermediates during fatty acid and polyketide synthesis, are difficult to visualise. Here, the authors developed a facile, Raman spectroscopy-based method to detect ACP-substrate interactions.