Tracking carrier protein motions with Raman spectroscopy

Acyl carrier proteins (ACPs), a universal and highly conserved carrier of acyl intermediates during fatty acid and polyketide synthesis, are difficult to visualise. Here, the authors developed a facile, Raman spectroscopy-based method to detect ACP-substrate interactions.

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Autores principales: Samuel C. Epstein, Adam R. Huff, Emily S. Winesett, Casey H. Londergan, Louise K. Charkoudian
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2019
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Acceso en línea:https://doaj.org/article/af029210b2084baead366317ac033fb1
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spelling oai:doaj.org-article:af029210b2084baead366317ac033fb12021-12-02T16:57:06ZTracking carrier protein motions with Raman spectroscopy10.1038/s41467-019-10184-22041-1723https://doaj.org/article/af029210b2084baead366317ac033fb12019-05-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-10184-2https://doaj.org/toc/2041-1723Acyl carrier proteins (ACPs), a universal and highly conserved carrier of acyl intermediates during fatty acid and polyketide synthesis, are difficult to visualise. Here, the authors developed a facile, Raman spectroscopy-based method to detect ACP-substrate interactions.Samuel C. EpsteinAdam R. HuffEmily S. WinesettCasey H. LonderganLouise K. CharkoudianNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-6 (2019)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Samuel C. Epstein
Adam R. Huff
Emily S. Winesett
Casey H. Londergan
Louise K. Charkoudian
Tracking carrier protein motions with Raman spectroscopy
description Acyl carrier proteins (ACPs), a universal and highly conserved carrier of acyl intermediates during fatty acid and polyketide synthesis, are difficult to visualise. Here, the authors developed a facile, Raman spectroscopy-based method to detect ACP-substrate interactions.
format article
author Samuel C. Epstein
Adam R. Huff
Emily S. Winesett
Casey H. Londergan
Louise K. Charkoudian
author_facet Samuel C. Epstein
Adam R. Huff
Emily S. Winesett
Casey H. Londergan
Louise K. Charkoudian
author_sort Samuel C. Epstein
title Tracking carrier protein motions with Raman spectroscopy
title_short Tracking carrier protein motions with Raman spectroscopy
title_full Tracking carrier protein motions with Raman spectroscopy
title_fullStr Tracking carrier protein motions with Raman spectroscopy
title_full_unstemmed Tracking carrier protein motions with Raman spectroscopy
title_sort tracking carrier protein motions with raman spectroscopy
publisher Nature Portfolio
publishDate 2019
url https://doaj.org/article/af029210b2084baead366317ac033fb1
work_keys_str_mv AT samuelcepstein trackingcarrierproteinmotionswithramanspectroscopy
AT adamrhuff trackingcarrierproteinmotionswithramanspectroscopy
AT emilyswinesett trackingcarrierproteinmotionswithramanspectroscopy
AT caseyhlondergan trackingcarrierproteinmotionswithramanspectroscopy
AT louisekcharkoudian trackingcarrierproteinmotionswithramanspectroscopy
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