Evaluation of the effect of filtered ultrafine particulate matter on bleomycin-induced lung fibrosis in a rat model using computed tomography, histopathologic analysis, and RNA sequencing

Abstract We aimed to investigate the effect of chronic particulate matter (PM) exposure on bleomycin-induced lung fibrosis in a rat model using chest CT, histopathologic evaluation, and RNA-sequencing. A bleomycin solution was intratracheally administrated to 20 male rats. For chronic PM exposure, a...

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Bibliographic Details
Main Authors: Cherry Kim, Sang Hoon Jeong, Jaeyoung Kim, Ja Young Kang, Yoon Jeong Nam, Ariunaa Togloom, Jaehyung Cha, Ki Yeol Lee, Chang Hyun Lee, Eun-Kee Park, Ju-Han Lee
Format: article
Language:EN
Published: Nature Portfolio 2021
Subjects:
R
Q
Online Access:https://doaj.org/article/af07f7552d7c4c518ef0a1ee9e5ec0cf
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