Identification and characterization of two novel viruses in ocular infections in reindeer.
A thorough understanding of virus diversity in wildlife provides epidemiological baseline information about pathogens. In this study, eye swab samples were obtained from semi-domesticated reindeer (Rangifertarandus tarandus) in Norway during an outbreak of infectious eye disease, possibly a very ear...
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Public Library of Science (PLoS)
2013
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oai:doaj.org-article:af1016ca93df4a47b8ccf7c3b28e20f12021-11-18T07:37:27ZIdentification and characterization of two novel viruses in ocular infections in reindeer.1932-620310.1371/journal.pone.0069711https://doaj.org/article/af1016ca93df4a47b8ccf7c3b28e20f12013-01-01T00:00:00Zhttps://www.ncbi.nlm.nih.gov/pmc/articles/pmid/23874987/?tool=EBIhttps://doaj.org/toc/1932-6203A thorough understanding of virus diversity in wildlife provides epidemiological baseline information about pathogens. In this study, eye swab samples were obtained from semi-domesticated reindeer (Rangifertarandus tarandus) in Norway during an outbreak of infectious eye disease, possibly a very early stage of infectious keratoconjunctivitis (IKC). Large scale molecular virus screening, based on host nucleic acid depletion, sequence-independent amplification and next-generation sequencing of partially purified viral nucleic acid, revealed the presence of a new papillomavirus in 2 out of 8 eye swab samples and a new betaherpesvirus in 3 out of 8 eye swab samples collected from animals with clinical signs and not in similar samples in 9 animals without clinical signs. Whether either virus was responsible for causing the clinical signs or in any respect was associated to the disease condition remains to be determined.Saskia L SmitsClaudia M E SchapendonkMarije van LeeuwenThijs KuikenRogier BodewesV Stalin RajBart L HaagmansCarlos G das NevesMorten TrylandAlbert D M E OsterhausPublic Library of Science (PLoS)articleMedicineRScienceQENPLoS ONE, Vol 8, Iss 7, p e69711 (2013) |
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DOAJ |
| collection |
DOAJ |
| language |
EN |
| topic |
Medicine R Science Q |
| spellingShingle |
Medicine R Science Q Saskia L Smits Claudia M E Schapendonk Marije van Leeuwen Thijs Kuiken Rogier Bodewes V Stalin Raj Bart L Haagmans Carlos G das Neves Morten Tryland Albert D M E Osterhaus Identification and characterization of two novel viruses in ocular infections in reindeer. |
| description |
A thorough understanding of virus diversity in wildlife provides epidemiological baseline information about pathogens. In this study, eye swab samples were obtained from semi-domesticated reindeer (Rangifertarandus tarandus) in Norway during an outbreak of infectious eye disease, possibly a very early stage of infectious keratoconjunctivitis (IKC). Large scale molecular virus screening, based on host nucleic acid depletion, sequence-independent amplification and next-generation sequencing of partially purified viral nucleic acid, revealed the presence of a new papillomavirus in 2 out of 8 eye swab samples and a new betaherpesvirus in 3 out of 8 eye swab samples collected from animals with clinical signs and not in similar samples in 9 animals without clinical signs. Whether either virus was responsible for causing the clinical signs or in any respect was associated to the disease condition remains to be determined. |
| format |
article |
| author |
Saskia L Smits Claudia M E Schapendonk Marije van Leeuwen Thijs Kuiken Rogier Bodewes V Stalin Raj Bart L Haagmans Carlos G das Neves Morten Tryland Albert D M E Osterhaus |
| author_facet |
Saskia L Smits Claudia M E Schapendonk Marije van Leeuwen Thijs Kuiken Rogier Bodewes V Stalin Raj Bart L Haagmans Carlos G das Neves Morten Tryland Albert D M E Osterhaus |
| author_sort |
Saskia L Smits |
| title |
Identification and characterization of two novel viruses in ocular infections in reindeer. |
| title_short |
Identification and characterization of two novel viruses in ocular infections in reindeer. |
| title_full |
Identification and characterization of two novel viruses in ocular infections in reindeer. |
| title_fullStr |
Identification and characterization of two novel viruses in ocular infections in reindeer. |
| title_full_unstemmed |
Identification and characterization of two novel viruses in ocular infections in reindeer. |
| title_sort |
identification and characterization of two novel viruses in ocular infections in reindeer. |
| publisher |
Public Library of Science (PLoS) |
| publishDate |
2013 |
| url |
https://doaj.org/article/af1016ca93df4a47b8ccf7c3b28e20f1 |
| work_keys_str_mv |
AT saskialsmits identificationandcharacterizationoftwonovelvirusesinocularinfectionsinreindeer AT claudiameschapendonk identificationandcharacterizationoftwonovelvirusesinocularinfectionsinreindeer AT marijevanleeuwen identificationandcharacterizationoftwonovelvirusesinocularinfectionsinreindeer AT thijskuiken identificationandcharacterizationoftwonovelvirusesinocularinfectionsinreindeer AT rogierbodewes identificationandcharacterizationoftwonovelvirusesinocularinfectionsinreindeer AT vstalinraj identificationandcharacterizationoftwonovelvirusesinocularinfectionsinreindeer AT bartlhaagmans identificationandcharacterizationoftwonovelvirusesinocularinfectionsinreindeer AT carlosgdasneves identificationandcharacterizationoftwonovelvirusesinocularinfectionsinreindeer AT mortentryland identificationandcharacterizationoftwonovelvirusesinocularinfectionsinreindeer AT albertdmeosterhaus identificationandcharacterizationoftwonovelvirusesinocularinfectionsinreindeer |
| _version_ |
1718423184002252800 |