Estrogen receptor β activation impairs prostatic regeneration by inducing apoptosis in murine and human stem/progenitor enriched cell populations.
Androgen depletion is the primary treatment for prostate disease; however, it fails to target residual castrate-resistant cells that are regenerative and cells of origin of prostate cancer. Estrogens, like androgens, regulate survival in prostatic cells, and the goal of this study was to determine t...
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Autores principales: | Shirin Hussain, Mitchell G Lawrence, Renea A Taylor, Camden Yeung-Wah Lo, APC BioResource, Mark Frydenberg, Stuart J Ellem, Luc Furic, Gail P Risbridger |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Public Library of Science (PLoS)
2012
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Materias: | |
Acceso en línea: | https://doaj.org/article/af2fe4a94dca42c6bb0b8c712ee49467 |
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