Poly(L-lactic acid) Reinforced with Hydroxyapatite and Tungsten Disulfide Nanotubes

Poly(L-lactic acid) (PLLA) is a biocompatible, biodegradable, and semi-crystalline polymer with numerous applications including food packaging, medical implants, stents, tissue engineering scaffolds, etc. Hydroxyapatite (HA) is the major component of natural bone. Conceptually, combining PLLA and HA...

Descripción completa

Guardado en:
Detalles Bibliográficos
Autores principales: Ofek Golan, Hila Shalom, Ifat Kaplan-Ashiri, Sidney R. Cohen, Yishay Feldman, Iddo Pinkas, Rakefet Ofek Almog, Alla Zak, Reshef Tenne
Formato: article
Lenguaje:EN
Publicado: MDPI AG 2021
Materias:
Acceso en línea:https://doaj.org/article/af3f3912ab2b423cbff7a105a2bb300d
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
id oai:doaj.org-article:af3f3912ab2b423cbff7a105a2bb300d
record_format dspace
spelling oai:doaj.org-article:af3f3912ab2b423cbff7a105a2bb300d2021-11-11T18:49:08ZPoly(L-lactic acid) Reinforced with Hydroxyapatite and Tungsten Disulfide Nanotubes10.3390/polym132138512073-4360https://doaj.org/article/af3f3912ab2b423cbff7a105a2bb300d2021-11-01T00:00:00Zhttps://www.mdpi.com/2073-4360/13/21/3851https://doaj.org/toc/2073-4360Poly(L-lactic acid) (PLLA) is a biocompatible, biodegradable, and semi-crystalline polymer with numerous applications including food packaging, medical implants, stents, tissue engineering scaffolds, etc. Hydroxyapatite (HA) is the major component of natural bone. Conceptually, combining PLLA and HA could produce a bioceramic suitable for implants and bone repair. However, this nanocomposite suffers from poor mechanical behavior under tensile strain. In this study, films of PLLA and HA were prepared with small amounts of nontoxic WS<sub>2</sub> nanotubes (INT-WS<sub>2</sub>). The structural aspects of the films were investigated via electron microscopy, X-ray diffraction, Raman microscopy, and infrared absorption spectroscopy. The mechanical properties were evaluated via tensile measurements, micro-hardness tests, and nanoindentation. The thermal properties were investigated via differential scanning calorimetry. The composite films exhibited improved mechanical and thermal properties compared to the films prepared from the PLLA and HA alone, which is advantageous for medical applications.Ofek GolanHila ShalomIfat Kaplan-AshiriSidney R. CohenYishay FeldmanIddo PinkasRakefet Ofek AlmogAlla ZakReshef TenneMDPI AGarticlePLLAhydroxyapatiteWS<sub>2</sub> nanotubesbiodegradable polymersmechanical propertiesOrganic chemistryQD241-441ENPolymers, Vol 13, Iss 3851, p 3851 (2021)
institution DOAJ
collection DOAJ
language EN
topic PLLA
hydroxyapatite
WS<sub>2</sub> nanotubes
biodegradable polymers
mechanical properties
Organic chemistry
QD241-441
spellingShingle PLLA
hydroxyapatite
WS<sub>2</sub> nanotubes
biodegradable polymers
mechanical properties
Organic chemistry
QD241-441
Ofek Golan
Hila Shalom
Ifat Kaplan-Ashiri
Sidney R. Cohen
Yishay Feldman
Iddo Pinkas
Rakefet Ofek Almog
Alla Zak
Reshef Tenne
Poly(L-lactic acid) Reinforced with Hydroxyapatite and Tungsten Disulfide Nanotubes
description Poly(L-lactic acid) (PLLA) is a biocompatible, biodegradable, and semi-crystalline polymer with numerous applications including food packaging, medical implants, stents, tissue engineering scaffolds, etc. Hydroxyapatite (HA) is the major component of natural bone. Conceptually, combining PLLA and HA could produce a bioceramic suitable for implants and bone repair. However, this nanocomposite suffers from poor mechanical behavior under tensile strain. In this study, films of PLLA and HA were prepared with small amounts of nontoxic WS<sub>2</sub> nanotubes (INT-WS<sub>2</sub>). The structural aspects of the films were investigated via electron microscopy, X-ray diffraction, Raman microscopy, and infrared absorption spectroscopy. The mechanical properties were evaluated via tensile measurements, micro-hardness tests, and nanoindentation. The thermal properties were investigated via differential scanning calorimetry. The composite films exhibited improved mechanical and thermal properties compared to the films prepared from the PLLA and HA alone, which is advantageous for medical applications.
format article
author Ofek Golan
Hila Shalom
Ifat Kaplan-Ashiri
Sidney R. Cohen
Yishay Feldman
Iddo Pinkas
Rakefet Ofek Almog
Alla Zak
Reshef Tenne
author_facet Ofek Golan
Hila Shalom
Ifat Kaplan-Ashiri
Sidney R. Cohen
Yishay Feldman
Iddo Pinkas
Rakefet Ofek Almog
Alla Zak
Reshef Tenne
author_sort Ofek Golan
title Poly(L-lactic acid) Reinforced with Hydroxyapatite and Tungsten Disulfide Nanotubes
title_short Poly(L-lactic acid) Reinforced with Hydroxyapatite and Tungsten Disulfide Nanotubes
title_full Poly(L-lactic acid) Reinforced with Hydroxyapatite and Tungsten Disulfide Nanotubes
title_fullStr Poly(L-lactic acid) Reinforced with Hydroxyapatite and Tungsten Disulfide Nanotubes
title_full_unstemmed Poly(L-lactic acid) Reinforced with Hydroxyapatite and Tungsten Disulfide Nanotubes
title_sort poly(l-lactic acid) reinforced with hydroxyapatite and tungsten disulfide nanotubes
publisher MDPI AG
publishDate 2021
url https://doaj.org/article/af3f3912ab2b423cbff7a105a2bb300d
work_keys_str_mv AT ofekgolan polyllacticacidreinforcedwithhydroxyapatiteandtungstendisulfidenanotubes
AT hilashalom polyllacticacidreinforcedwithhydroxyapatiteandtungstendisulfidenanotubes
AT ifatkaplanashiri polyllacticacidreinforcedwithhydroxyapatiteandtungstendisulfidenanotubes
AT sidneyrcohen polyllacticacidreinforcedwithhydroxyapatiteandtungstendisulfidenanotubes
AT yishayfeldman polyllacticacidreinforcedwithhydroxyapatiteandtungstendisulfidenanotubes
AT iddopinkas polyllacticacidreinforcedwithhydroxyapatiteandtungstendisulfidenanotubes
AT rakefetofekalmog polyllacticacidreinforcedwithhydroxyapatiteandtungstendisulfidenanotubes
AT allazak polyllacticacidreinforcedwithhydroxyapatiteandtungstendisulfidenanotubes
AT resheftenne polyllacticacidreinforcedwithhydroxyapatiteandtungstendisulfidenanotubes
_version_ 1718431719537770496