Mycolic acid modification by the mmaA4 gene of M. tuberculosis modulates IL-12 production.

Mycobacterium tuberculosis has evolved many strategies to evade elimination by the host immune system, including the selective repression of macrophage IL-12p40 production. To identify the M. tuberculosis genes responsible for this aspect of immune evasion, we used a macrophage cell line expressing...

Full description

Saved in:
Bibliographic Details
Main Authors: Dee N Dao, Kari Sweeney, Tsungda Hsu, Sudagar S Gurcha, Ivan P Nascimento, Dan Roshevsky, Gurdyal S Besra, John Chan, Steven A Porcelli, William R Jacobs
Format: article
Language:EN
Published: Public Library of Science (PLoS) 2008
Subjects:
Online Access:https://doaj.org/article/af43775a7c4e45428bfb7a3ddf3d3ba7
Tags: Add Tag
No Tags, Be the first to tag this record!