Breakthrough Infections of E484K-Harboring SARS-CoV-2 Delta Variant, Lombardy, Italy

The Delta variant of concern of severe acute respiratory syndrome coronavirus 2 is dominant worldwide. We report a case cluster caused by Delta sublineage B.1.617.2 harboring the mutation E484K in Italy during July 11–July 29, 2021. This mutation appears to affect immune response and vaccine effica...

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Autores principales:	Andreina Baj, Federica Novazzi, Renee Pasciuta, Angelo Genoni, Francesca Drago Ferrante, Marilena Valli, Michele Partenope, Rosalia Tripiciano, Andrea Ciserchia, Giuseppe Catanoso, Daniele Focosi, Fabrizio Maggi
Formato:	article
Lenguaje:	EN
Publicado:	Centers for Disease Control and Prevention 2021
Materias:	SARS-CoV-2 COVID-19 coronavirus disease severe acute respiratory syndrome coronavirus 2 viruses respiratory infections Medicine R Infectious and parasitic diseases RC109-216
Acceso en línea:	https://doaj.org/article/af4384603743496e98f99540d6211fd2
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spelling	oai:doaj.org-article:af4384603743496e98f99540d6211fd22021-11-22T12:59:04ZBreakthrough Infections of E484K-Harboring SARS-CoV-2 Delta Variant, Lombardy, Italy10.3201/eid2712.2117921080-60401080-6059https://doaj.org/article/af4384603743496e98f99540d6211fd22021-12-01T00:00:00Zhttps://wwwnc.cdc.gov/eid/article/27/12/21-1792_articlehttps://doaj.org/toc/1080-6040https://doaj.org/toc/1080-6059 The Delta variant of concern of severe acute respiratory syndrome coronavirus 2 is dominant worldwide. We report a case cluster caused by Delta sublineage B.1.617.2 harboring the mutation E484K in Italy during July 11–July 29, 2021. This mutation appears to affect immune response and vaccine efficacy; monitoring its appearance is urgent. Andreina BajFederica NovazziRenee PasciutaAngelo GenoniFrancesca Drago FerranteMarilena ValliMichele PartenopeRosalia TripicianoAndrea CiserchiaGiuseppe CatanosoDaniele FocosiFabrizio MaggiCenters for Disease Control and PreventionarticleSARS-CoV-2COVID-19coronavirus diseasesevere acute respiratory syndrome coronavirus 2virusesrespiratory infectionsMedicineRInfectious and parasitic diseasesRC109-216ENEmerging Infectious Diseases, Vol 27, Iss 12, Pp 3180-3182 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	SARS-CoV-2 COVID-19 coronavirus disease severe acute respiratory syndrome coronavirus 2 viruses respiratory infections Medicine R Infectious and parasitic diseases RC109-216
spellingShingle	SARS-CoV-2 COVID-19 coronavirus disease severe acute respiratory syndrome coronavirus 2 viruses respiratory infections Medicine R Infectious and parasitic diseases RC109-216 Andreina Baj Federica Novazzi Renee Pasciuta Angelo Genoni Francesca Drago Ferrante Marilena Valli Michele Partenope Rosalia Tripiciano Andrea Ciserchia Giuseppe Catanoso Daniele Focosi Fabrizio Maggi Breakthrough Infections of E484K-Harboring SARS-CoV-2 Delta Variant, Lombardy, Italy
description	The Delta variant of concern of severe acute respiratory syndrome coronavirus 2 is dominant worldwide. We report a case cluster caused by Delta sublineage B.1.617.2 harboring the mutation E484K in Italy during July 11–July 29, 2021. This mutation appears to affect immune response and vaccine efficacy; monitoring its appearance is urgent.
format	article
author	Andreina Baj Federica Novazzi Renee Pasciuta Angelo Genoni Francesca Drago Ferrante Marilena Valli Michele Partenope Rosalia Tripiciano Andrea Ciserchia Giuseppe Catanoso Daniele Focosi Fabrizio Maggi
author_facet	Andreina Baj Federica Novazzi Renee Pasciuta Angelo Genoni Francesca Drago Ferrante Marilena Valli Michele Partenope Rosalia Tripiciano Andrea Ciserchia Giuseppe Catanoso Daniele Focosi Fabrizio Maggi
author_sort	Andreina Baj
title	Breakthrough Infections of E484K-Harboring SARS-CoV-2 Delta Variant, Lombardy, Italy
title_short	Breakthrough Infections of E484K-Harboring SARS-CoV-2 Delta Variant, Lombardy, Italy
title_full	Breakthrough Infections of E484K-Harboring SARS-CoV-2 Delta Variant, Lombardy, Italy
title_fullStr	Breakthrough Infections of E484K-Harboring SARS-CoV-2 Delta Variant, Lombardy, Italy
title_full_unstemmed	Breakthrough Infections of E484K-Harboring SARS-CoV-2 Delta Variant, Lombardy, Italy
title_sort	breakthrough infections of e484k-harboring sars-cov-2 delta variant, lombardy, italy
publisher	Centers for Disease Control and Prevention
publishDate	2021
url	https://doaj.org/article/af4384603743496e98f99540d6211fd2
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Breakthrough Infections of E484K-Harboring SARS-CoV-2 Delta Variant, Lombardy, Italy

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