Intestinal-derived FGF15 protects against deleterious effects of vertical sleeve gastrectomy in mice

Intestinal-derived FGF15 protects against deleterious effects of vertical sleeve gastrectomy in mice

The mechanisms that mediate the effects of weight loss surgeries such as vertical sleeve gastrectomy (VSG) are incompletely understood. Here the authors show that intestinal FGF15 is necessary to improve glucose tolerance and to prevent the loss of muscle and bone mass after VSG, potentially via pro...

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Autores principales: Nadejda Bozadjieva-Kramer, Jae Hoon Shin, Yikai Shao, Ruth Gutierrez-Aguilar, Ziru Li, Kristy M. Heppner, Samuel Chiang, Sara G. Vargo, Katrina Granger, Darleen A. Sandoval, Ormond A. MacDougald, Randy J. Seeley
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Science
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Acceso en línea:https://doaj.org/article/af44be2074044e2db785c4c8cb983aeb
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