High-throughput chromatin accessibility profiling at single-cell resolution

Single-cell chromatin accessibility is a promising means to identify regulatory programs in mixtures of cells. Here the authors describe µ-ATAC-seq, a low-cost method that can generate thousands of accessibility profiles per day.

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Autores principales:	Anja Mezger, Sandy Klemm, Ishminder Mann, Kara Brower, Alain Mir, Magnolia Bostick, Andrew Farmer, Polly Fordyce, Sten Linnarsson, William Greenleaf
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2018
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/af490554bcce4098a9e163206ed9a85f
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spelling	oai:doaj.org-article:af490554bcce4098a9e163206ed9a85f2021-12-02T16:49:35ZHigh-throughput chromatin accessibility profiling at single-cell resolution10.1038/s41467-018-05887-x2041-1723https://doaj.org/article/af490554bcce4098a9e163206ed9a85f2018-09-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-05887-xhttps://doaj.org/toc/2041-1723Single-cell chromatin accessibility is a promising means to identify regulatory programs in mixtures of cells. Here the authors describe µ-ATAC-seq, a low-cost method that can generate thousands of accessibility profiles per day.Anja MezgerSandy KlemmIshminder MannKara BrowerAlain MirMagnolia BostickAndrew FarmerPolly FordyceSten LinnarssonWilliam GreenleafNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-6 (2018)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Anja Mezger Sandy Klemm Ishminder Mann Kara Brower Alain Mir Magnolia Bostick Andrew Farmer Polly Fordyce Sten Linnarsson William Greenleaf High-throughput chromatin accessibility profiling at single-cell resolution
description	Single-cell chromatin accessibility is a promising means to identify regulatory programs in mixtures of cells. Here the authors describe µ-ATAC-seq, a low-cost method that can generate thousands of accessibility profiles per day.
format	article
author	Anja Mezger Sandy Klemm Ishminder Mann Kara Brower Alain Mir Magnolia Bostick Andrew Farmer Polly Fordyce Sten Linnarsson William Greenleaf
author_facet	Anja Mezger Sandy Klemm Ishminder Mann Kara Brower Alain Mir Magnolia Bostick Andrew Farmer Polly Fordyce Sten Linnarsson William Greenleaf
author_sort	Anja Mezger
title	High-throughput chromatin accessibility profiling at single-cell resolution
title_short	High-throughput chromatin accessibility profiling at single-cell resolution
title_full	High-throughput chromatin accessibility profiling at single-cell resolution
title_fullStr	High-throughput chromatin accessibility profiling at single-cell resolution
title_full_unstemmed	High-throughput chromatin accessibility profiling at single-cell resolution
title_sort	high-throughput chromatin accessibility profiling at single-cell resolution
publisher	Nature Portfolio
publishDate	2018
url	https://doaj.org/article/af490554bcce4098a9e163206ed9a85f
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High-throughput chromatin accessibility profiling at single-cell resolution

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