Viral fibrotic scoring and drug screen based on MAPK activity uncovers EGFR as a key regulator of COVID-19 fibrosis

Abstract Understanding the molecular basis of fibrosis, the lethal complication of COVID-19, is urgent. By the analysis of RNA-sequencing data of SARS-CoV-2-infected cells combined with data mining we identified genes involved in COVID-19 progression. To characterize their implication in the fibrosi...

Full description

Saved in:
Bibliographic Details
Main Authors: Elmira R. Vagapova, Timofey D. Lebedev, Vladimir S. Prassolov
Format: article
Language:EN
Published: Nature Portfolio 2021
Subjects:
R
Q
Online Access:https://doaj.org/article/af657faedb774b16b9c79f1776b9032d
Tags: Add Tag
No Tags, Be the first to tag this record!