3D tumor spheroid microarray for high-throughput, high-content natural killer cell-mediated cytotoxicity
Gopal et al. present a high-throughput platform for analysing the cytotoxicity of various combination therapies against established cancer cell lines, focusing especially on NK cell-mediated cytotoxicity. The presented method is reported to successfully mimic the tumour microenvironment and demonstr...
Guardado en:
| Autores principales: | , , , , , |
|---|---|
| Formato: | article |
| Lenguaje: | EN |
| Publicado: |
Nature Portfolio
2021
|
| Materias: | |
| Acceso en línea: | https://doaj.org/article/af67cea50a174afea27e38c42066450c |
| Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
| Sumario: | Gopal et al. present a high-throughput platform for analysing the cytotoxicity of various combination therapies against established cancer cell lines, focusing especially on NK cell-mediated cytotoxicity. The presented method is reported to successfully mimic the tumour microenvironment and demonstrates NK cell-mediated cell cytotoxicity using small molecule chemotherapeutic drugs in combination with monoclonal antibodies. |
|---|