Global pairwise RNA interaction landscapes reveal core features of protein recognition

RNA–protein interactions often depend on the recognition of extended RNA elements but the identification of these motifs is challenging. Here, the authors present a global integrated approach to analyze RNA–protein binding landscapes, mapping extended RNA interaction motifs for four RNA-binding prot...

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Auteurs principaux:	Qin Zhou, Nikesh Kunder, José Alberto De la Paz, Alexandra E. Lasley, Vandita D. Bhat, Faruck Morcos, Zachary T. Campbell
Format:	article
Langue:	EN
Publié:	Nature Portfolio 2018
Sujets:	Science Q
Accès en ligne:	https://doaj.org/article/af6c4a7edad74e59bf7fe4351b97e630
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spelling	oai:doaj.org-article:af6c4a7edad74e59bf7fe4351b97e6302021-12-02T16:49:23ZGlobal pairwise RNA interaction landscapes reveal core features of protein recognition10.1038/s41467-018-04729-02041-1723https://doaj.org/article/af6c4a7edad74e59bf7fe4351b97e6302018-06-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-04729-0https://doaj.org/toc/2041-1723RNA–protein interactions often depend on the recognition of extended RNA elements but the identification of these motifs is challenging. Here, the authors present a global integrated approach to analyze RNA–protein binding landscapes, mapping extended RNA interaction motifs for four RNA-binding proteins.Qin ZhouNikesh KunderJosé Alberto De la PazAlexandra E. LasleyVandita D. BhatFaruck MorcosZachary T. CampbellNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-10 (2018)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Qin Zhou Nikesh Kunder José Alberto De la Paz Alexandra E. Lasley Vandita D. Bhat Faruck Morcos Zachary T. Campbell Global pairwise RNA interaction landscapes reveal core features of protein recognition
description	RNA–protein interactions often depend on the recognition of extended RNA elements but the identification of these motifs is challenging. Here, the authors present a global integrated approach to analyze RNA–protein binding landscapes, mapping extended RNA interaction motifs for four RNA-binding proteins.
format	article
author	Qin Zhou Nikesh Kunder José Alberto De la Paz Alexandra E. Lasley Vandita D. Bhat Faruck Morcos Zachary T. Campbell
author_facet	Qin Zhou Nikesh Kunder José Alberto De la Paz Alexandra E. Lasley Vandita D. Bhat Faruck Morcos Zachary T. Campbell
author_sort	Qin Zhou
title	Global pairwise RNA interaction landscapes reveal core features of protein recognition
title_short	Global pairwise RNA interaction landscapes reveal core features of protein recognition
title_full	Global pairwise RNA interaction landscapes reveal core features of protein recognition
title_fullStr	Global pairwise RNA interaction landscapes reveal core features of protein recognition
title_full_unstemmed	Global pairwise RNA interaction landscapes reveal core features of protein recognition
title_sort	global pairwise rna interaction landscapes reveal core features of protein recognition
publisher	Nature Portfolio
publishDate	2018
url	https://doaj.org/article/af6c4a7edad74e59bf7fe4351b97e630
work_keys_str_mv	AT qinzhou globalpairwisernainteractionlandscapesrevealcorefeaturesofproteinrecognition AT nikeshkunder globalpairwisernainteractionlandscapesrevealcorefeaturesofproteinrecognition AT josealbertodelapaz globalpairwisernainteractionlandscapesrevealcorefeaturesofproteinrecognition AT alexandraelasley globalpairwisernainteractionlandscapesrevealcorefeaturesofproteinrecognition AT vanditadbhat globalpairwisernainteractionlandscapesrevealcorefeaturesofproteinrecognition AT faruckmorcos globalpairwisernainteractionlandscapesrevealcorefeaturesofproteinrecognition AT zacharytcampbell globalpairwisernainteractionlandscapesrevealcorefeaturesofproteinrecognition
_version_	1718383355634909184

Global pairwise RNA interaction landscapes reveal core features of protein recognition

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