A large family of Dscam genes with tandemly arrayed 5′ cassettes in Chelicerata

Drosophila Dscam1 and vertebrate clustered protocadherins (Pcdh) are known for their extraordinary isoform diversity. Here authors identify a shortened Dscam gene family in Chelicerata, which displays homology to Drosophila Dscam1, and employs splicing patterns similar to that of vertebrate Pcdhs.

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Auteurs principaux: Yuan Yue, Yijun Meng, Hongru Ma, Shouqing Hou, Guozheng Cao, Weiling Hong, Yang Shi, Pengjuan Guo, Baoping Liu, Feng Shi, Yun Yang, Yongfeng Jin
Format: article
Langue:EN
Publié: Nature Portfolio 2016
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Accès en ligne:https://doaj.org/article/af7267f08247480ab3d6efa6f9b6ee2f
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Résumé:Drosophila Dscam1 and vertebrate clustered protocadherins (Pcdh) are known for their extraordinary isoform diversity. Here authors identify a shortened Dscam gene family in Chelicerata, which displays homology to Drosophila Dscam1, and employs splicing patterns similar to that of vertebrate Pcdhs.