Modulating notochordal differentiation of human induced pluripotent stem cells using natural nucleus pulposus tissue matrix.
Human induced pluripotent stem cells (hiPSCs) can differentiate into notochordal cell (NC)-like cells when cultured in the presence of natural porcine nucleus pulposus (NP) tissue matrix. The method promises massive production of high-quality, functional cells to treat degenerative intervertebral di...
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Autores principales: | Yongxing Liu, Mohamed N Rahaman, B Sonny Bal |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Public Library of Science (PLoS)
2014
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Materias: | |
Acceso en línea: | https://doaj.org/article/af75ab5a2e624742a2522ac902f5bdfb |
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