Pre-plaque conformational changes in Alzheimer’s disease-linked Aβ and APP

Studying the physiological confirmation of amyloid β (Aβ) and amyloid precursor protein (APP) often uses techniques that could disrupt their conformation. Here, the authors use non-destructive microscopy approaches to study the confirmation of Aβ and APP in mouse models of Alzheimer’s disease.

Guardado en:

Detalles Bibliográficos
Autores principales:	O. Klementieva, K. Willén, I. Martinsson, B. Israelsson, A. Engdahl, J. Cladera, P. Uvdal, G. K. Gouras
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2017
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/af765fa52d0140b79804721f5a08b6fa
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:af765fa52d0140b79804721f5a08b6fa
record_format	dspace
spelling	oai:doaj.org-article:af765fa52d0140b79804721f5a08b6fa2021-12-02T14:42:08ZPre-plaque conformational changes in Alzheimer’s disease-linked Aβ and APP10.1038/ncomms147262041-1723https://doaj.org/article/af765fa52d0140b79804721f5a08b6fa2017-03-01T00:00:00Zhttps://doi.org/10.1038/ncomms14726https://doaj.org/toc/2041-1723Studying the physiological confirmation of amyloid β (Aβ) and amyloid precursor protein (APP) often uses techniques that could disrupt their conformation. Here, the authors use non-destructive microscopy approaches to study the confirmation of Aβ and APP in mouse models of Alzheimer’s disease.O. KlementievaK. WillénI. MartinssonB. IsraelssonA. EngdahlJ. CladeraP. UvdalG. K. GourasNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-9 (2017)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q O. Klementieva K. Willén I. Martinsson B. Israelsson A. Engdahl J. Cladera P. Uvdal G. K. Gouras Pre-plaque conformational changes in Alzheimer’s disease-linked Aβ and APP
description	Studying the physiological confirmation of amyloid β (Aβ) and amyloid precursor protein (APP) often uses techniques that could disrupt their conformation. Here, the authors use non-destructive microscopy approaches to study the confirmation of Aβ and APP in mouse models of Alzheimer’s disease.
format	article
author	O. Klementieva K. Willén I. Martinsson B. Israelsson A. Engdahl J. Cladera P. Uvdal G. K. Gouras
author_facet	O. Klementieva K. Willén I. Martinsson B. Israelsson A. Engdahl J. Cladera P. Uvdal G. K. Gouras
author_sort	O. Klementieva
title	Pre-plaque conformational changes in Alzheimer’s disease-linked Aβ and APP
title_short	Pre-plaque conformational changes in Alzheimer’s disease-linked Aβ and APP
title_full	Pre-plaque conformational changes in Alzheimer’s disease-linked Aβ and APP
title_fullStr	Pre-plaque conformational changes in Alzheimer’s disease-linked Aβ and APP
title_full_unstemmed	Pre-plaque conformational changes in Alzheimer’s disease-linked Aβ and APP
title_sort	pre-plaque conformational changes in alzheimer’s disease-linked aβ and app
publisher	Nature Portfolio
publishDate	2017
url	https://doaj.org/article/af765fa52d0140b79804721f5a08b6fa
work_keys_str_mv	AT oklementieva preplaqueconformationalchangesinalzheimersdiseaselinkedabandapp AT kwillen preplaqueconformationalchangesinalzheimersdiseaselinkedabandapp AT imartinsson preplaqueconformationalchangesinalzheimersdiseaselinkedabandapp AT bisraelsson preplaqueconformationalchangesinalzheimersdiseaselinkedabandapp AT aengdahl preplaqueconformationalchangesinalzheimersdiseaselinkedabandapp AT jcladera preplaqueconformationalchangesinalzheimersdiseaselinkedabandapp AT puvdal preplaqueconformationalchangesinalzheimersdiseaselinkedabandapp AT gkgouras preplaqueconformationalchangesinalzheimersdiseaselinkedabandapp
_version_	1718389772183928832

Pre-plaque conformational changes in Alzheimer’s disease-linked Aβ and APP

Ejemplares similares