Pre-plaque conformational changes in Alzheimer’s disease-linked Aβ and APP

Pre-plaque conformational changes in Alzheimer’s disease-linked Aβ and APP

Studying the physiological confirmation of amyloid β (Aβ) and amyloid precursor protein (APP) often uses techniques that could disrupt their conformation. Here, the authors use non-destructive microscopy approaches to study the confirmation of Aβ and APP in mouse models of Alzheimer’s disease.

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Autores principales: O. Klementieva, K. Willén, I. Martinsson, B. Israelsson, A. Engdahl, J. Cladera, P. Uvdal, G. K. Gouras
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2017
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Science
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Acceso en línea:https://doaj.org/article/af765fa52d0140b79804721f5a08b6fa
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