The BIN1 rs744373 SNP is associated with increased tau-PET levels and impaired memory

The BIN1 rs744373 SNP is associated with increased tau-PET levels and impaired memory

The BIN1 SNP rs744373 is associated with higher CSF tau and phosphorylated tau levels. Here the authors show, using PET imaging, that this SNP is associated with tau accumulation in the brain as well as impaired memory in older individuals without dementia.

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Autores principales: Nicolai Franzmeier, Anna Rubinski, Julia Neitzel, Michael Ewers, The Alzheimer’s Disease Neuroimaging Initiative (ADNI)
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2019
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Acceso en línea:https://doaj.org/article/af9ef677104b492a9ea299f7988cef93
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spelling oai:doaj.org-article:af9ef677104b492a9ea299f7988cef932021-12-02T14:38:42ZThe BIN1 rs744373 SNP is associated with increased tau-PET levels and impaired memory10.1038/s41467-019-09564-52041-1723https://doaj.org/article/af9ef677104b492a9ea299f7988cef932019-04-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-09564-5https://doaj.org/toc/2041-1723The BIN1 SNP rs744373 is associated with higher CSF tau and phosphorylated tau levels. Here the authors show, using PET imaging, that this SNP is associated with tau accumulation in the brain as well as impaired memory in older individuals without dementia.Nicolai FranzmeierAnna RubinskiJulia NeitzelMichael EwersThe Alzheimer’s Disease Neuroimaging Initiative (ADNI)Nature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-12 (2019)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Nicolai Franzmeier
Anna Rubinski
Julia Neitzel
Michael Ewers
The Alzheimer’s Disease Neuroimaging Initiative (ADNI)
The BIN1 rs744373 SNP is associated with increased tau-PET levels and impaired memory
description The BIN1 SNP rs744373 is associated with higher CSF tau and phosphorylated tau levels. Here the authors show, using PET imaging, that this SNP is associated with tau accumulation in the brain as well as impaired memory in older individuals without dementia.
format article
author Nicolai Franzmeier
Anna Rubinski
Julia Neitzel
Michael Ewers
The Alzheimer’s Disease Neuroimaging Initiative (ADNI)
author_facet Nicolai Franzmeier
Anna Rubinski
Julia Neitzel
Michael Ewers
The Alzheimer’s Disease Neuroimaging Initiative (ADNI)
author_sort Nicolai Franzmeier
title The BIN1 rs744373 SNP is associated with increased tau-PET levels and impaired memory
title_short The BIN1 rs744373 SNP is associated with increased tau-PET levels and impaired memory
title_full The BIN1 rs744373 SNP is associated with increased tau-PET levels and impaired memory
title_fullStr The BIN1 rs744373 SNP is associated with increased tau-PET levels and impaired memory
title_full_unstemmed The BIN1 rs744373 SNP is associated with increased tau-PET levels and impaired memory
title_sort bin1 rs744373 snp is associated with increased tau-pet levels and impaired memory
publisher Nature Portfolio
publishDate 2019
url https://doaj.org/article/af9ef677104b492a9ea299f7988cef93
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