The BIN1 rs744373 SNP is associated with increased tau-PET levels and impaired memory

The BIN1 SNP rs744373 is associated with higher CSF tau and phosphorylated tau levels. Here the authors show, using PET imaging, that this SNP is associated with tau accumulation in the brain as well as impaired memory in older individuals without dementia.

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Detalles Bibliográficos
Autores principales: Nicolai Franzmeier, Anna Rubinski, Julia Neitzel, Michael Ewers, The Alzheimer’s Disease Neuroimaging Initiative (ADNI)
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2019
Materias:
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Acceso en línea:https://doaj.org/article/af9ef677104b492a9ea299f7988cef93
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