Cationic amino acid transporters play key roles in the survival and transmission of apicomplexan parasites
Apicomplexans are parasites that use membrane transporters to scavenge essential nutrients from the host. Here the authors identify and characterize two apicomplexans transporters showing that these are crucial for cationic amino acid uptake, parasite survival and virulence.
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Nature Portfolio
2017
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oai:doaj.org-article:af9f4f91b04841bdb2ffbb97deef12282021-12-02T17:06:29ZCationic amino acid transporters play key roles in the survival and transmission of apicomplexan parasites10.1038/ncomms144552041-1723https://doaj.org/article/af9f4f91b04841bdb2ffbb97deef12282017-02-01T00:00:00Zhttps://doi.org/10.1038/ncomms14455https://doaj.org/toc/2041-1723Apicomplexans are parasites that use membrane transporters to scavenge essential nutrients from the host. Here the authors identify and characterize two apicomplexans transporters showing that these are crucial for cationic amino acid uptake, parasite survival and virulence.Esther RajendranSanduni V. HapuarachchiCatherine M. MillerStephen J. FairweatherYeping CaiNicholas C. SmithIan A. CockburnStefan BröerKiaran KirkGiel G. van DoorenNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-13 (2017) |
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Science Q |
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Science Q Esther Rajendran Sanduni V. Hapuarachchi Catherine M. Miller Stephen J. Fairweather Yeping Cai Nicholas C. Smith Ian A. Cockburn Stefan Bröer Kiaran Kirk Giel G. van Dooren Cationic amino acid transporters play key roles in the survival and transmission of apicomplexan parasites |
description |
Apicomplexans are parasites that use membrane transporters to scavenge essential nutrients from the host. Here the authors identify and characterize two apicomplexans transporters showing that these are crucial for cationic amino acid uptake, parasite survival and virulence. |
format |
article |
author |
Esther Rajendran Sanduni V. Hapuarachchi Catherine M. Miller Stephen J. Fairweather Yeping Cai Nicholas C. Smith Ian A. Cockburn Stefan Bröer Kiaran Kirk Giel G. van Dooren |
author_facet |
Esther Rajendran Sanduni V. Hapuarachchi Catherine M. Miller Stephen J. Fairweather Yeping Cai Nicholas C. Smith Ian A. Cockburn Stefan Bröer Kiaran Kirk Giel G. van Dooren |
author_sort |
Esther Rajendran |
title |
Cationic amino acid transporters play key roles in the survival and transmission of apicomplexan parasites |
title_short |
Cationic amino acid transporters play key roles in the survival and transmission of apicomplexan parasites |
title_full |
Cationic amino acid transporters play key roles in the survival and transmission of apicomplexan parasites |
title_fullStr |
Cationic amino acid transporters play key roles in the survival and transmission of apicomplexan parasites |
title_full_unstemmed |
Cationic amino acid transporters play key roles in the survival and transmission of apicomplexan parasites |
title_sort |
cationic amino acid transporters play key roles in the survival and transmission of apicomplexan parasites |
publisher |
Nature Portfolio |
publishDate |
2017 |
url |
https://doaj.org/article/af9f4f91b04841bdb2ffbb97deef1228 |
work_keys_str_mv |
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