Cationic amino acid transporters play key roles in the survival and transmission of apicomplexan parasites

Apicomplexans are parasites that use membrane transporters to scavenge essential nutrients from the host. Here the authors identify and characterize two apicomplexans transporters showing that these are crucial for cationic amino acid uptake, parasite survival and virulence.

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Autores principales: Esther Rajendran, Sanduni V. Hapuarachchi, Catherine M. Miller, Stephen J. Fairweather, Yeping Cai, Nicholas C. Smith, Ian A. Cockburn, Stefan Bröer, Kiaran Kirk, Giel G. van Dooren
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Lenguaje:EN
Publicado: Nature Portfolio 2017
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Acceso en línea:https://doaj.org/article/af9f4f91b04841bdb2ffbb97deef1228
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spelling oai:doaj.org-article:af9f4f91b04841bdb2ffbb97deef12282021-12-02T17:06:29ZCationic amino acid transporters play key roles in the survival and transmission of apicomplexan parasites10.1038/ncomms144552041-1723https://doaj.org/article/af9f4f91b04841bdb2ffbb97deef12282017-02-01T00:00:00Zhttps://doi.org/10.1038/ncomms14455https://doaj.org/toc/2041-1723Apicomplexans are parasites that use membrane transporters to scavenge essential nutrients from the host. Here the authors identify and characterize two apicomplexans transporters showing that these are crucial for cationic amino acid uptake, parasite survival and virulence.Esther RajendranSanduni V. HapuarachchiCatherine M. MillerStephen J. FairweatherYeping CaiNicholas C. SmithIan A. CockburnStefan BröerKiaran KirkGiel G. van DoorenNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-13 (2017)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Esther Rajendran
Sanduni V. Hapuarachchi
Catherine M. Miller
Stephen J. Fairweather
Yeping Cai
Nicholas C. Smith
Ian A. Cockburn
Stefan Bröer
Kiaran Kirk
Giel G. van Dooren
Cationic amino acid transporters play key roles in the survival and transmission of apicomplexan parasites
description Apicomplexans are parasites that use membrane transporters to scavenge essential nutrients from the host. Here the authors identify and characterize two apicomplexans transporters showing that these are crucial for cationic amino acid uptake, parasite survival and virulence.
format article
author Esther Rajendran
Sanduni V. Hapuarachchi
Catherine M. Miller
Stephen J. Fairweather
Yeping Cai
Nicholas C. Smith
Ian A. Cockburn
Stefan Bröer
Kiaran Kirk
Giel G. van Dooren
author_facet Esther Rajendran
Sanduni V. Hapuarachchi
Catherine M. Miller
Stephen J. Fairweather
Yeping Cai
Nicholas C. Smith
Ian A. Cockburn
Stefan Bröer
Kiaran Kirk
Giel G. van Dooren
author_sort Esther Rajendran
title Cationic amino acid transporters play key roles in the survival and transmission of apicomplexan parasites
title_short Cationic amino acid transporters play key roles in the survival and transmission of apicomplexan parasites
title_full Cationic amino acid transporters play key roles in the survival and transmission of apicomplexan parasites
title_fullStr Cationic amino acid transporters play key roles in the survival and transmission of apicomplexan parasites
title_full_unstemmed Cationic amino acid transporters play key roles in the survival and transmission of apicomplexan parasites
title_sort cationic amino acid transporters play key roles in the survival and transmission of apicomplexan parasites
publisher Nature Portfolio
publishDate 2017
url https://doaj.org/article/af9f4f91b04841bdb2ffbb97deef1228
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