Common DNA methylation dynamics in endometriod adenocarcinoma and glioblastoma suggest universal epigenomic alterations in tumorigenesis

Jennifer Karlow et al. characterize the DNA methylation changes in two unrelated cancer types. They find that both cancers show methylation changes in regulatory regions corresponding to the cancer’s tissue of origin, suggesting that loss of cellular identity may be an important step in tumorigenese...

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Autores principales:	Jennifer A. Karlow, Benpeng Miao, Xiaoyun Xing, Ting Wang, Bo Zhang
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Biology (General) QH301-705.5
Acceso en línea:	https://doaj.org/article/afa1954161d74d21afb4cf3c2c3d2ba0
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spelling	oai:doaj.org-article:afa1954161d74d21afb4cf3c2c3d2ba02021-12-02T15:52:54ZCommon DNA methylation dynamics in endometriod adenocarcinoma and glioblastoma suggest universal epigenomic alterations in tumorigenesis10.1038/s42003-021-02094-12399-3642https://doaj.org/article/afa1954161d74d21afb4cf3c2c3d2ba02021-05-01T00:00:00Zhttps://doi.org/10.1038/s42003-021-02094-1https://doaj.org/toc/2399-3642Jennifer Karlow et al. characterize the DNA methylation changes in two unrelated cancer types. They find that both cancers show methylation changes in regulatory regions corresponding to the cancer’s tissue of origin, suggesting that loss of cellular identity may be an important step in tumorigeneses shared across cancers.Jennifer A. KarlowBenpeng MiaoXiaoyun XingTing WangBo ZhangNature PortfolioarticleBiology (General)QH301-705.5ENCommunications Biology, Vol 4, Iss 1, Pp 1-16 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Biology (General) QH301-705.5
spellingShingle	Biology (General) QH301-705.5 Jennifer A. Karlow Benpeng Miao Xiaoyun Xing Ting Wang Bo Zhang Common DNA methylation dynamics in endometriod adenocarcinoma and glioblastoma suggest universal epigenomic alterations in tumorigenesis
description	Jennifer Karlow et al. characterize the DNA methylation changes in two unrelated cancer types. They find that both cancers show methylation changes in regulatory regions corresponding to the cancer’s tissue of origin, suggesting that loss of cellular identity may be an important step in tumorigeneses shared across cancers.
format	article
author	Jennifer A. Karlow Benpeng Miao Xiaoyun Xing Ting Wang Bo Zhang
author_facet	Jennifer A. Karlow Benpeng Miao Xiaoyun Xing Ting Wang Bo Zhang
author_sort	Jennifer A. Karlow
title	Common DNA methylation dynamics in endometriod adenocarcinoma and glioblastoma suggest universal epigenomic alterations in tumorigenesis
title_short	Common DNA methylation dynamics in endometriod adenocarcinoma and glioblastoma suggest universal epigenomic alterations in tumorigenesis
title_full	Common DNA methylation dynamics in endometriod adenocarcinoma and glioblastoma suggest universal epigenomic alterations in tumorigenesis
title_fullStr	Common DNA methylation dynamics in endometriod adenocarcinoma and glioblastoma suggest universal epigenomic alterations in tumorigenesis
title_full_unstemmed	Common DNA methylation dynamics in endometriod adenocarcinoma and glioblastoma suggest universal epigenomic alterations in tumorigenesis
title_sort	common dna methylation dynamics in endometriod adenocarcinoma and glioblastoma suggest universal epigenomic alterations in tumorigenesis
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/afa1954161d74d21afb4cf3c2c3d2ba0
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Common DNA methylation dynamics in endometriod adenocarcinoma and glioblastoma suggest universal epigenomic alterations in tumorigenesis

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