Aerobic Exercise in the Management of Metabolic Dysfunction Associated Fatty Liver Disease

Mariana Verdelho Machado1,2 1Serviço de Gastrenterologia, Hospital de Vila Franca de Xira, Vila Franca de Xira, Portugal; 2Faculdade de Medicina, Universidade de Lisboa, Lisboa, PortugalCorrespondence: Mariana Verdelho MachadoFaculdade de Medicina, Universidade de Lisboa, Avenida Professor Egas Moni...

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Autor principal:	Machado MV
Formato:	article
Lenguaje:	EN
Publicado:	Dove Medical Press 2021
Materias:	metabolic dysfunction-associated fatty liver disease physical activity aerobic exercise. Specialties of internal medicine RC581-951
Acceso en línea:	https://doaj.org/article/afa519329cea4625bb81f2f722c0d62b
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spelling	oai:doaj.org-article:afa519329cea4625bb81f2f722c0d62b2021-12-02T17:07:18ZAerobic Exercise in the Management of Metabolic Dysfunction Associated Fatty Liver Disease1178-7007https://doaj.org/article/afa519329cea4625bb81f2f722c0d62b2021-08-01T00:00:00Zhttps://www.dovepress.com/aerobic-exercise-in-the-management-of-metabolic-dysfunction-associated-peer-reviewed-fulltext-article-DMSOhttps://doaj.org/toc/1178-7007Mariana Verdelho Machado1,2 1Serviço de Gastrenterologia, Hospital de Vila Franca de Xira, Vila Franca de Xira, Portugal; 2Faculdade de Medicina, Universidade de Lisboa, Lisboa, PortugalCorrespondence: Mariana Verdelho MachadoFaculdade de Medicina, Universidade de Lisboa, Avenida Professor Egas Moniz, Lisboa, 1649-035, PortugalTel +35 1912620306Email mverdelhomachado@gmail.comAbstract: Sedentarism is the pandemic of modern times. It is associated with several medical conditions including obesity, type 2 diabetes mellitus, cardiovascular diseases and also liver disease, particularly metabolic dysfunction associated fatty liver disease (MAFLD). In an era when MAFLD is the most prevalent chronic liver disease worldwide, whilst no pharmacological therapy has been approved for it, exercise has proved to be effective in improving liver steatosis. Interestingly, exercise decreases liver fat even in the absence of weight loss. The challenge for the clinician is to motivate the obese patient with MAFLD, and associated co-morbidities, who has crystallized a sedentary behavior, at times when every need is at the distance of a click on the Internet, and the entire world can be visited behind a screen. In this review, the aggregate evidence on the mechanisms and effects of exercise in the management of MAFLD is summarized, with simple recommendations for everyday clinical practice.Keywords: metabolic dysfunction-associated fatty liver disease, physical activity, aerobic exerciseMachado MVDove Medical Pressarticlemetabolic dysfunction-associated fatty liver diseasephysical activityaerobic exercise.Specialties of internal medicineRC581-951ENDiabetes, Metabolic Syndrome and Obesity: Targets and Therapy, Vol Volume 14, Pp 3627-3645 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	metabolic dysfunction-associated fatty liver disease physical activity aerobic exercise. Specialties of internal medicine RC581-951
spellingShingle	metabolic dysfunction-associated fatty liver disease physical activity aerobic exercise. Specialties of internal medicine RC581-951 Machado MV Aerobic Exercise in the Management of Metabolic Dysfunction Associated Fatty Liver Disease
description	Mariana Verdelho Machado1,2 1Serviço de Gastrenterologia, Hospital de Vila Franca de Xira, Vila Franca de Xira, Portugal; 2Faculdade de Medicina, Universidade de Lisboa, Lisboa, PortugalCorrespondence: Mariana Verdelho MachadoFaculdade de Medicina, Universidade de Lisboa, Avenida Professor Egas Moniz, Lisboa, 1649-035, PortugalTel +35 1912620306Email mverdelhomachado@gmail.comAbstract: Sedentarism is the pandemic of modern times. It is associated with several medical conditions including obesity, type 2 diabetes mellitus, cardiovascular diseases and also liver disease, particularly metabolic dysfunction associated fatty liver disease (MAFLD). In an era when MAFLD is the most prevalent chronic liver disease worldwide, whilst no pharmacological therapy has been approved for it, exercise has proved to be effective in improving liver steatosis. Interestingly, exercise decreases liver fat even in the absence of weight loss. The challenge for the clinician is to motivate the obese patient with MAFLD, and associated co-morbidities, who has crystallized a sedentary behavior, at times when every need is at the distance of a click on the Internet, and the entire world can be visited behind a screen. In this review, the aggregate evidence on the mechanisms and effects of exercise in the management of MAFLD is summarized, with simple recommendations for everyday clinical practice.Keywords: metabolic dysfunction-associated fatty liver disease, physical activity, aerobic exercise
format	article
author	Machado MV
author_facet	Machado MV
author_sort	Machado MV
title	Aerobic Exercise in the Management of Metabolic Dysfunction Associated Fatty Liver Disease
title_short	Aerobic Exercise in the Management of Metabolic Dysfunction Associated Fatty Liver Disease
title_full	Aerobic Exercise in the Management of Metabolic Dysfunction Associated Fatty Liver Disease
title_fullStr	Aerobic Exercise in the Management of Metabolic Dysfunction Associated Fatty Liver Disease
title_full_unstemmed	Aerobic Exercise in the Management of Metabolic Dysfunction Associated Fatty Liver Disease
title_sort	aerobic exercise in the management of metabolic dysfunction associated fatty liver disease
publisher	Dove Medical Press
publishDate	2021
url	https://doaj.org/article/afa519329cea4625bb81f2f722c0d62b
work_keys_str_mv	AT machadomv aerobicexerciseinthemanagementofmetabolicdysfunctionassociatedfattyliverdisease
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Aerobic Exercise in the Management of Metabolic Dysfunction Associated Fatty Liver Disease

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