Bronchoscopy-Guided Intervention Therapy With Extracorporeal Membrane Oxygenation Support for Relapsing Polychondritis With Severe Tracheobronchomalacia: A Case Report and Literature Review
Relapsing polychondritis is an immune disorder of unknown etiology involving multiple systems that is characterized by persistent inflammation and destruction of cartilage, including the ears, nose, costal, joint, and airways. Airway involvement caused by relapsing polychondritis is common, and trac...
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Frontiers Media S.A.
2021
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oai:doaj.org-article:afb2d0a12ede45238ff3d61722d5c7c32021-11-30T11:56:48ZBronchoscopy-Guided Intervention Therapy With Extracorporeal Membrane Oxygenation Support for Relapsing Polychondritis With Severe Tracheobronchomalacia: A Case Report and Literature Review2296-858X10.3389/fmed.2021.695505https://doaj.org/article/afb2d0a12ede45238ff3d61722d5c7c32021-11-01T00:00:00Zhttps://www.frontiersin.org/articles/10.3389/fmed.2021.695505/fullhttps://doaj.org/toc/2296-858XRelapsing polychondritis is an immune disorder of unknown etiology involving multiple systems that is characterized by persistent inflammation and destruction of cartilage, including the ears, nose, costal, joint, and airways. Airway involvement caused by relapsing polychondritis is common, and tracheobronchomalacia is the most serious complication, which is life-threatening. Currently, the exact mechanism of relapsing polychondritis with tracheobronchomalacia is unknown. Although glucocorticoids and immunosuppressive agents are administered, failures often occur. Currently, bronchoscopy-guided intervention therapy used in tracheobronchomalacia caused by chronic obstructive pulmonary disease or other etiology has gradually increased, but bronchoscopy-guided intervention therapy with extracorporeal membrane oxygenation assist used in tracheobronchomalacia caused by relapsing polychondritis has not been reported. Here, we report a case of relapsing polychondritis with severe tracheobronchomalacia. Although drug therapy was provided and airway stent implantation was performed, the tracheal stenosis was further aggravated. Because conventional anesthesia and mechanical ventilation cannot meet the needs of bronchoscopy-guided intervention therapy or guarantee sufficient safety. The intervention treatment was performed with the support of extracorporeal membrane oxygenation, which was successfully completed without obvious complications. The symptoms were significantly improved, and the patient was discharged uneventfully.Pengcheng ZhouBing FuChuantao ZhangKeling ChenQianming XiaWenjun TangWei YuWenhui HuangFrontiers Media S.A.articleextracorporeal membrane oxygenationrelapsing polychondritistracheobronchomalaciasevere airway stenosisbronchoscopyinterventional therapyMedicine (General)R5-920ENFrontiers in Medicine, Vol 8 (2021) |
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extracorporeal membrane oxygenation relapsing polychondritis tracheobronchomalacia severe airway stenosis bronchoscopy interventional therapy Medicine (General) R5-920 |
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extracorporeal membrane oxygenation relapsing polychondritis tracheobronchomalacia severe airway stenosis bronchoscopy interventional therapy Medicine (General) R5-920 Pengcheng Zhou Bing Fu Chuantao Zhang Keling Chen Qianming Xia Wenjun Tang Wei Yu Wenhui Huang Bronchoscopy-Guided Intervention Therapy With Extracorporeal Membrane Oxygenation Support for Relapsing Polychondritis With Severe Tracheobronchomalacia: A Case Report and Literature Review |
description |
Relapsing polychondritis is an immune disorder of unknown etiology involving multiple systems that is characterized by persistent inflammation and destruction of cartilage, including the ears, nose, costal, joint, and airways. Airway involvement caused by relapsing polychondritis is common, and tracheobronchomalacia is the most serious complication, which is life-threatening. Currently, the exact mechanism of relapsing polychondritis with tracheobronchomalacia is unknown. Although glucocorticoids and immunosuppressive agents are administered, failures often occur. Currently, bronchoscopy-guided intervention therapy used in tracheobronchomalacia caused by chronic obstructive pulmonary disease or other etiology has gradually increased, but bronchoscopy-guided intervention therapy with extracorporeal membrane oxygenation assist used in tracheobronchomalacia caused by relapsing polychondritis has not been reported. Here, we report a case of relapsing polychondritis with severe tracheobronchomalacia. Although drug therapy was provided and airway stent implantation was performed, the tracheal stenosis was further aggravated. Because conventional anesthesia and mechanical ventilation cannot meet the needs of bronchoscopy-guided intervention therapy or guarantee sufficient safety. The intervention treatment was performed with the support of extracorporeal membrane oxygenation, which was successfully completed without obvious complications. The symptoms were significantly improved, and the patient was discharged uneventfully. |
format |
article |
author |
Pengcheng Zhou Bing Fu Chuantao Zhang Keling Chen Qianming Xia Wenjun Tang Wei Yu Wenhui Huang |
author_facet |
Pengcheng Zhou Bing Fu Chuantao Zhang Keling Chen Qianming Xia Wenjun Tang Wei Yu Wenhui Huang |
author_sort |
Pengcheng Zhou |
title |
Bronchoscopy-Guided Intervention Therapy With Extracorporeal Membrane Oxygenation Support for Relapsing Polychondritis With Severe Tracheobronchomalacia: A Case Report and Literature Review |
title_short |
Bronchoscopy-Guided Intervention Therapy With Extracorporeal Membrane Oxygenation Support for Relapsing Polychondritis With Severe Tracheobronchomalacia: A Case Report and Literature Review |
title_full |
Bronchoscopy-Guided Intervention Therapy With Extracorporeal Membrane Oxygenation Support for Relapsing Polychondritis With Severe Tracheobronchomalacia: A Case Report and Literature Review |
title_fullStr |
Bronchoscopy-Guided Intervention Therapy With Extracorporeal Membrane Oxygenation Support for Relapsing Polychondritis With Severe Tracheobronchomalacia: A Case Report and Literature Review |
title_full_unstemmed |
Bronchoscopy-Guided Intervention Therapy With Extracorporeal Membrane Oxygenation Support for Relapsing Polychondritis With Severe Tracheobronchomalacia: A Case Report and Literature Review |
title_sort |
bronchoscopy-guided intervention therapy with extracorporeal membrane oxygenation support for relapsing polychondritis with severe tracheobronchomalacia: a case report and literature review |
publisher |
Frontiers Media S.A. |
publishDate |
2021 |
url |
https://doaj.org/article/afb2d0a12ede45238ff3d61722d5c7c3 |
work_keys_str_mv |
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