NirA Is an Alternative Nitrite Reductase from Pseudomonas aeruginosa with Potential as an Antivirulence Target

The emergence of widespread antimicrobial resistance has led to the need for development of novel therapeutic interventions. Antivirulence strategies are an attractive alternative to classic antimicrobial therapy; however, they require identification of new specific targets which can be exploited i...

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Autores principales:	Samuel Fenn, Jean-Frédéric Dubern, Cristina Cigana, Maura De Simone, James Lazenby, Mario Juhas, Stephan Schwager, Irene Bianconi, Gerd Döring, Jonas Elmsley, Leo Eberl, Paul Williams, Alessandra Bragonzi, Miguel Cámara
Formato:	article
Lenguaje:	EN
Publicado:	American Society for Microbiology 2021
Materias:	Microbiology QR1-502
Acceso en línea:	https://doaj.org/article/afb4e30e21634b5e896ebe24694c0eaa
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spelling	oai:doaj.org-article:afb4e30e21634b5e896ebe24694c0eaa2021-11-03T18:56:09ZNirA Is an Alternative Nitrite Reductase from Pseudomonas aeruginosa with Potential as an Antivirulence Target2150-751110.1128/mBio.00207-21https://doaj.org/article/afb4e30e21634b5e896ebe24694c0eaa2021-04-01T00:00:00Zhttps://journals.asm.org/doi/10.1128/mBio.00207-21https://doaj.org/toc/2150-7511 The emergence of widespread antimicrobial resistance has led to the need for development of novel therapeutic interventions. Antivirulence strategies are an attractive alternative to classic antimicrobial therapy; however, they require identification of new specific targets which can be exploited in drug discovery programs.Samuel FennJean-Frédéric DubernCristina CiganaMaura De SimoneJames LazenbyMario JuhasStephan SchwagerIrene BianconiGerd DöringJonas ElmsleyLeo EberlPaul WilliamsAlessandra BragonziMiguel CámaraAmerican Society for MicrobiologyarticleMicrobiologyQR1-502ENmBio, Vol 12, Iss 2 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Microbiology QR1-502
spellingShingle	Microbiology QR1-502 Samuel Fenn Jean-Frédéric Dubern Cristina Cigana Maura De Simone James Lazenby Mario Juhas Stephan Schwager Irene Bianconi Gerd Döring Jonas Elmsley Leo Eberl Paul Williams Alessandra Bragonzi Miguel Cámara NirA Is an Alternative Nitrite Reductase from Pseudomonas aeruginosa with Potential as an Antivirulence Target
description	The emergence of widespread antimicrobial resistance has led to the need for development of novel therapeutic interventions. Antivirulence strategies are an attractive alternative to classic antimicrobial therapy; however, they require identification of new specific targets which can be exploited in drug discovery programs.
format	article
author	Samuel Fenn Jean-Frédéric Dubern Cristina Cigana Maura De Simone James Lazenby Mario Juhas Stephan Schwager Irene Bianconi Gerd Döring Jonas Elmsley Leo Eberl Paul Williams Alessandra Bragonzi Miguel Cámara
author_facet	Samuel Fenn Jean-Frédéric Dubern Cristina Cigana Maura De Simone James Lazenby Mario Juhas Stephan Schwager Irene Bianconi Gerd Döring Jonas Elmsley Leo Eberl Paul Williams Alessandra Bragonzi Miguel Cámara
author_sort	Samuel Fenn
title	NirA Is an Alternative Nitrite Reductase from Pseudomonas aeruginosa with Potential as an Antivirulence Target
title_short	NirA Is an Alternative Nitrite Reductase from Pseudomonas aeruginosa with Potential as an Antivirulence Target
title_full	NirA Is an Alternative Nitrite Reductase from Pseudomonas aeruginosa with Potential as an Antivirulence Target
title_fullStr	NirA Is an Alternative Nitrite Reductase from Pseudomonas aeruginosa with Potential as an Antivirulence Target
title_full_unstemmed	NirA Is an Alternative Nitrite Reductase from Pseudomonas aeruginosa with Potential as an Antivirulence Target
title_sort	nira is an alternative nitrite reductase from pseudomonas aeruginosa with potential as an antivirulence target
publisher	American Society for Microbiology
publishDate	2021
url	https://doaj.org/article/afb4e30e21634b5e896ebe24694c0eaa
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NirA Is an Alternative Nitrite Reductase from Pseudomonas aeruginosa with Potential as an Antivirulence Target

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