Macromolecular-clustered facial amphiphilic antimicrobials

Bacterial infections and antibiotic resistance are an increasing concern for the world. Here the authors report a class of cationic antimicrobial polymers that cluster local facial amphiphilicity from repeating units to enhance interactions with bacterial membranes without requiring a high unfavorab...

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Autores principales: Md Anisur Rahman, Marpe Bam, Edgar Luat, Moumita Sharmin Jui, Mitra S. Ganewatta, Tinom Shokfai, Mitzi Nagarkatti, Alan W. Decho, Chuanbing Tang
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2018
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Acceso en línea:https://doaj.org/article/afbf5155b08341869a558dffb39340ec
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spelling oai:doaj.org-article:afbf5155b08341869a558dffb39340ec2021-12-02T17:32:16ZMacromolecular-clustered facial amphiphilic antimicrobials10.1038/s41467-018-07651-72041-1723https://doaj.org/article/afbf5155b08341869a558dffb39340ec2018-12-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-07651-7https://doaj.org/toc/2041-1723Bacterial infections and antibiotic resistance are an increasing concern for the world. Here the authors report a class of cationic antimicrobial polymers that cluster local facial amphiphilicity from repeating units to enhance interactions with bacterial membranes without requiring a high unfavorable entropic loss.Md Anisur RahmanMarpe BamEdgar LuatMoumita Sharmin JuiMitra S. GanewattaTinom ShokfaiMitzi NagarkattiAlan W. DechoChuanbing TangNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-10 (2018)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Md Anisur Rahman
Marpe Bam
Edgar Luat
Moumita Sharmin Jui
Mitra S. Ganewatta
Tinom Shokfai
Mitzi Nagarkatti
Alan W. Decho
Chuanbing Tang
Macromolecular-clustered facial amphiphilic antimicrobials
description Bacterial infections and antibiotic resistance are an increasing concern for the world. Here the authors report a class of cationic antimicrobial polymers that cluster local facial amphiphilicity from repeating units to enhance interactions with bacterial membranes without requiring a high unfavorable entropic loss.
format article
author Md Anisur Rahman
Marpe Bam
Edgar Luat
Moumita Sharmin Jui
Mitra S. Ganewatta
Tinom Shokfai
Mitzi Nagarkatti
Alan W. Decho
Chuanbing Tang
author_facet Md Anisur Rahman
Marpe Bam
Edgar Luat
Moumita Sharmin Jui
Mitra S. Ganewatta
Tinom Shokfai
Mitzi Nagarkatti
Alan W. Decho
Chuanbing Tang
author_sort Md Anisur Rahman
title Macromolecular-clustered facial amphiphilic antimicrobials
title_short Macromolecular-clustered facial amphiphilic antimicrobials
title_full Macromolecular-clustered facial amphiphilic antimicrobials
title_fullStr Macromolecular-clustered facial amphiphilic antimicrobials
title_full_unstemmed Macromolecular-clustered facial amphiphilic antimicrobials
title_sort macromolecular-clustered facial amphiphilic antimicrobials
publisher Nature Portfolio
publishDate 2018
url https://doaj.org/article/afbf5155b08341869a558dffb39340ec
work_keys_str_mv AT mdanisurrahman macromolecularclusteredfacialamphiphilicantimicrobials
AT marpebam macromolecularclusteredfacialamphiphilicantimicrobials
AT edgarluat macromolecularclusteredfacialamphiphilicantimicrobials
AT moumitasharminjui macromolecularclusteredfacialamphiphilicantimicrobials
AT mitrasganewatta macromolecularclusteredfacialamphiphilicantimicrobials
AT tinomshokfai macromolecularclusteredfacialamphiphilicantimicrobials
AT mitzinagarkatti macromolecularclusteredfacialamphiphilicantimicrobials
AT alanwdecho macromolecularclusteredfacialamphiphilicantimicrobials
AT chuanbingtang macromolecularclusteredfacialamphiphilicantimicrobials
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