Lipid peroxidation and antioxidant system in menopausal women with insomnia

According to the current data, most menopausal women have reduced life quality and one of the main criteria is sleep quality. It is well known, that sleep loss may cause oxidative stress. The aim of this study was to assess lipid peroxidation and antioxidant system in postmenopausal women with insom...

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Autor principal:	N. V. Semyonova
Formato:	article
Lenguaje:	RU
Publicado:	Scientific Сentre for Family Health and Human Reproduction Problems 2016
Materias:	lipid peroxidation antioxidant defense insomnia postmenopause Science Q
Acceso en línea:	https://doaj.org/article/afca9d8d5a1f4da5ad87f7a1eb8f8d3d
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spelling	oai:doaj.org-article:afca9d8d5a1f4da5ad87f7a1eb8f8d3d2021-11-23T06:14:34ZLipid peroxidation and antioxidant system in menopausal women with insomnia2541-94202587-959610.12737/article_590823a46a7b46.99413563https://doaj.org/article/afca9d8d5a1f4da5ad87f7a1eb8f8d3d2016-05-01T00:00:00Zhttps://www.actabiomedica.ru/jour/article/view/191https://doaj.org/toc/2541-9420https://doaj.org/toc/2587-9596According to the current data, most menopausal women have reduced life quality and one of the main criteria is sleep quality. It is well known, that sleep loss may cause oxidative stress. The aim of this study was to assess lipid peroxidation and antioxidant system in postmenopausal women with insomnia. Materials and methods: 41 postmenopausal women (18 patients with insomnia, 23 women without insomnia (control)) were examined. Sleep disorders were assessed by using sleep questionnaire (Stanford Sleep Research Center, USA), Epworth Sleepiness Scale, Insomnia Severity Index. The materials for biochemical studies were blood plasma and red cells. Lipid peroxidation and antioxidant system parameters by spectrophotometric and fluorometric methods were determined. Statistical analysis was performed by non-parametric test. The study results showed increase primary products levels in patients with insomnia compared with the control group. Main and control group antioxidant system parameters have no differences. Oxidative stress coefficient in group with insomnia higher than control. Conclusions: insomnia in postmenopausal women is associated with the development of oxidative stress.N. V. SemyonovaScientific Сentre for Family Health and Human Reproduction Problemsarticlelipid peroxidationantioxidant defenseinsomniapostmenopauseScienceQRUActa Biomedica Scientifica, Vol 1, Iss 3(2), Pp 74-77 (2016)
institution	DOAJ
collection	DOAJ
language	RU
topic	lipid peroxidation antioxidant defense insomnia postmenopause Science Q
spellingShingle	lipid peroxidation antioxidant defense insomnia postmenopause Science Q N. V. Semyonova Lipid peroxidation and antioxidant system in menopausal women with insomnia
description	According to the current data, most menopausal women have reduced life quality and one of the main criteria is sleep quality. It is well known, that sleep loss may cause oxidative stress. The aim of this study was to assess lipid peroxidation and antioxidant system in postmenopausal women with insomnia. Materials and methods: 41 postmenopausal women (18 patients with insomnia, 23 women without insomnia (control)) were examined. Sleep disorders were assessed by using sleep questionnaire (Stanford Sleep Research Center, USA), Epworth Sleepiness Scale, Insomnia Severity Index. The materials for biochemical studies were blood plasma and red cells. Lipid peroxidation and antioxidant system parameters by spectrophotometric and fluorometric methods were determined. Statistical analysis was performed by non-parametric test. The study results showed increase primary products levels in patients with insomnia compared with the control group. Main and control group antioxidant system parameters have no differences. Oxidative stress coefficient in group with insomnia higher than control. Conclusions: insomnia in postmenopausal women is associated with the development of oxidative stress.
format	article
author	N. V. Semyonova
author_facet	N. V. Semyonova
author_sort	N. V. Semyonova
title	Lipid peroxidation and antioxidant system in menopausal women with insomnia
title_short	Lipid peroxidation and antioxidant system in menopausal women with insomnia
title_full	Lipid peroxidation and antioxidant system in menopausal women with insomnia
title_fullStr	Lipid peroxidation and antioxidant system in menopausal women with insomnia
title_full_unstemmed	Lipid peroxidation and antioxidant system in menopausal women with insomnia
title_sort	lipid peroxidation and antioxidant system in menopausal women with insomnia
publisher	Scientific Сentre for Family Health and Human Reproduction Problems
publishDate	2016
url	https://doaj.org/article/afca9d8d5a1f4da5ad87f7a1eb8f8d3d
work_keys_str_mv	AT nvsemyonova lipidperoxidationandantioxidantsysteminmenopausalwomenwithinsomnia
_version_	1718417091312222208

Lipid peroxidation and antioxidant system in menopausal women with insomnia

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