Biomechanical characterization of human temporal muscle fascia in uniaxial tensile tests for graft purposes in duraplasty

Abstract The human temporal muscle fascia (TMF) is used frequently as a graft material for duraplasty. Encompassing biomechanical analyses of TMF are lacking, impeding a well-grounded biomechanical comparison of the TMF to other graft materials used for duraplasty, including the dura mater itself. I...

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Main Authors:	Johann Zwirner, Benjamin Ondruschka, Mario Scholze, Gundula Schulze-Tanzil, Niels Hammer
Format:	article
Language:	EN
Published:	Nature Portfolio 2021
Subjects:	Medicine R Science Q
Online Access:	https://doaj.org/article/afd229d759c94a428a6e8bd3ac03fe08
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spelling	oai:doaj.org-article:afd229d759c94a428a6e8bd3ac03fe082021-12-02T15:23:39ZBiomechanical characterization of human temporal muscle fascia in uniaxial tensile tests for graft purposes in duraplasty10.1038/s41598-020-80448-12045-2322https://doaj.org/article/afd229d759c94a428a6e8bd3ac03fe082021-01-01T00:00:00Zhttps://doi.org/10.1038/s41598-020-80448-1https://doaj.org/toc/2045-2322Abstract The human temporal muscle fascia (TMF) is used frequently as a graft material for duraplasty. Encompassing biomechanical analyses of TMF are lacking, impeding a well-grounded biomechanical comparison of the TMF to other graft materials used for duraplasty, including the dura mater itself. In this study, we investigated the biomechanical properties of 74 human TMF samples in comparison to an age-matched group of dura mater samples. The TMF showed an elastic modulus of 36 ± 19 MPa, an ultimate tensile strength of 3.6 ± 1.7 MPa, a maximum force of 16 ± 8 N, a maximum strain of 13 ± 4% and a strain at failure of 17 ± 6%. Post-mortem interval correlated weakly with elastic modulus (r = 0.255, p = 0.048) and the strain at failure (r = − 0.306, p = 0.022) for TMF. The age of the donors did not reveal significant correlations to the TMF mechanical parameters. Compared to the dura mater, the here investigated TMF showed a significantly lower elastic modulus and ultimate tensile strength, but a larger strain at failure. The human TMF with a post-mortem interval of up to 146 h may be considered a mechanically suitable graft material for duraplasty when stored at a temperature of 4 °C.Johann ZwirnerBenjamin OndruschkaMario ScholzeGundula Schulze-TanzilNiels HammerNature PortfolioarticleMedicineRScienceQENScientific Reports, Vol 11, Iss 1, Pp 1-11 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Johann Zwirner Benjamin Ondruschka Mario Scholze Gundula Schulze-Tanzil Niels Hammer Biomechanical characterization of human temporal muscle fascia in uniaxial tensile tests for graft purposes in duraplasty
description	Abstract The human temporal muscle fascia (TMF) is used frequently as a graft material for duraplasty. Encompassing biomechanical analyses of TMF are lacking, impeding a well-grounded biomechanical comparison of the TMF to other graft materials used for duraplasty, including the dura mater itself. In this study, we investigated the biomechanical properties of 74 human TMF samples in comparison to an age-matched group of dura mater samples. The TMF showed an elastic modulus of 36 ± 19 MPa, an ultimate tensile strength of 3.6 ± 1.7 MPa, a maximum force of 16 ± 8 N, a maximum strain of 13 ± 4% and a strain at failure of 17 ± 6%. Post-mortem interval correlated weakly with elastic modulus (r = 0.255, p = 0.048) and the strain at failure (r = − 0.306, p = 0.022) for TMF. The age of the donors did not reveal significant correlations to the TMF mechanical parameters. Compared to the dura mater, the here investigated TMF showed a significantly lower elastic modulus and ultimate tensile strength, but a larger strain at failure. The human TMF with a post-mortem interval of up to 146 h may be considered a mechanically suitable graft material for duraplasty when stored at a temperature of 4 °C.
format	article
author	Johann Zwirner Benjamin Ondruschka Mario Scholze Gundula Schulze-Tanzil Niels Hammer
author_facet	Johann Zwirner Benjamin Ondruschka Mario Scholze Gundula Schulze-Tanzil Niels Hammer
author_sort	Johann Zwirner
title	Biomechanical characterization of human temporal muscle fascia in uniaxial tensile tests for graft purposes in duraplasty
title_short	Biomechanical characterization of human temporal muscle fascia in uniaxial tensile tests for graft purposes in duraplasty
title_full	Biomechanical characterization of human temporal muscle fascia in uniaxial tensile tests for graft purposes in duraplasty
title_fullStr	Biomechanical characterization of human temporal muscle fascia in uniaxial tensile tests for graft purposes in duraplasty
title_full_unstemmed	Biomechanical characterization of human temporal muscle fascia in uniaxial tensile tests for graft purposes in duraplasty
title_sort	biomechanical characterization of human temporal muscle fascia in uniaxial tensile tests for graft purposes in duraplasty
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/afd229d759c94a428a6e8bd3ac03fe08
work_keys_str_mv	AT johannzwirner biomechanicalcharacterizationofhumantemporalmusclefasciainuniaxialtensiletestsforgraftpurposesinduraplasty AT benjaminondruschka biomechanicalcharacterizationofhumantemporalmusclefasciainuniaxialtensiletestsforgraftpurposesinduraplasty AT marioscholze biomechanicalcharacterizationofhumantemporalmusclefasciainuniaxialtensiletestsforgraftpurposesinduraplasty AT gundulaschulzetanzil biomechanicalcharacterizationofhumantemporalmusclefasciainuniaxialtensiletestsforgraftpurposesinduraplasty AT nielshammer biomechanicalcharacterizationofhumantemporalmusclefasciainuniaxialtensiletestsforgraftpurposesinduraplasty
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Biomechanical characterization of human temporal muscle fascia in uniaxial tensile tests for graft purposes in duraplasty

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