An unusual presentation of chronic lymphocytic leukemia

Chronic lymphocytic leukemia/small lymphocytic lymphoma (CLL/SLL) is a B-cell lymphocytic neoplasm with indolent clinical course. If identified early, observation is opted. Many variables lead to the initiation of treatment. Authors describe a 62-year-old male presenting with shortness of breath and...

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Autores principales:	Dinesh Atwal, Mihir Raval, Belal Firwana, Jeanette Ramos, Appalanaidu Sasapu
Formato:	article
Lenguaje:	EN
Publicado:	Thieme Medical and Scientific Publishers Pvt. Ltd. 2017
Materias:	chronic lymphocytic leukemia hyperleukocytosis leukostasis Medicine R
Acceso en línea:	https://doaj.org/article/afe53fafc617425aa29efae42c663f21
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spelling	oai:doaj.org-article:afe53fafc617425aa29efae42c663f212021-12-02T17:05:54ZAn unusual presentation of chronic lymphocytic leukemia2231-07702249-446410.4103/ajm.AJM_171_16https://doaj.org/article/afe53fafc617425aa29efae42c663f212017-07-01T00:00:00Zhttp://www.thieme-connect.de/DOI/DOI?10.4103/ajm.AJM_171_16https://doaj.org/toc/2231-0770https://doaj.org/toc/2249-4464Chronic lymphocytic leukemia/small lymphocytic lymphoma (CLL/SLL) is a B-cell lymphocytic neoplasm with indolent clinical course. If identified early, observation is opted. Many variables lead to the initiation of treatment. Authors describe a 62-year-old male presenting with shortness of breath and found to have white cell count of 1360 × 109/L and subsequently was diagnosed with CLL/SLL. The patient received leukapheresis along with tumor lysis treatment and systemic chemotherapy with fludarabine, cyclophosphamide, and rituximab regimen. His course was complicated with deep venous thrombosis, extensive cutaneous, and sinus mucosa involvement by CLL/SLL. The patient clinically improved and on follow-up clinic visits documented normalization of his white cell counts. The case report brings up a rare presentation of CLL/SLL with such an extreme high white cell count, leukostasis symptoms and extramedullary involvement of disease and encourages providers to be vigilant of rare presentation of CLL/SLL.Dinesh AtwalMihir RavalBelal FirwanaJeanette RamosAppalanaidu SasapuThieme Medical and Scientific Publishers Pvt. Ltd.articlechronic lymphocytic leukemiahyperleukocytosisleukostasisMedicineRENAvicenna Journal of Medicine, Vol 07, Iss 03, Pp 133-136 (2017)
institution	DOAJ
collection	DOAJ
language	EN
topic	chronic lymphocytic leukemia hyperleukocytosis leukostasis Medicine R
spellingShingle	chronic lymphocytic leukemia hyperleukocytosis leukostasis Medicine R Dinesh Atwal Mihir Raval Belal Firwana Jeanette Ramos Appalanaidu Sasapu An unusual presentation of chronic lymphocytic leukemia
description	Chronic lymphocytic leukemia/small lymphocytic lymphoma (CLL/SLL) is a B-cell lymphocytic neoplasm with indolent clinical course. If identified early, observation is opted. Many variables lead to the initiation of treatment. Authors describe a 62-year-old male presenting with shortness of breath and found to have white cell count of 1360 × 109/L and subsequently was diagnosed with CLL/SLL. The patient received leukapheresis along with tumor lysis treatment and systemic chemotherapy with fludarabine, cyclophosphamide, and rituximab regimen. His course was complicated with deep venous thrombosis, extensive cutaneous, and sinus mucosa involvement by CLL/SLL. The patient clinically improved and on follow-up clinic visits documented normalization of his white cell counts. The case report brings up a rare presentation of CLL/SLL with such an extreme high white cell count, leukostasis symptoms and extramedullary involvement of disease and encourages providers to be vigilant of rare presentation of CLL/SLL.
format	article
author	Dinesh Atwal Mihir Raval Belal Firwana Jeanette Ramos Appalanaidu Sasapu
author_facet	Dinesh Atwal Mihir Raval Belal Firwana Jeanette Ramos Appalanaidu Sasapu
author_sort	Dinesh Atwal
title	An unusual presentation of chronic lymphocytic leukemia
title_short	An unusual presentation of chronic lymphocytic leukemia
title_full	An unusual presentation of chronic lymphocytic leukemia
title_fullStr	An unusual presentation of chronic lymphocytic leukemia
title_full_unstemmed	An unusual presentation of chronic lymphocytic leukemia
title_sort	unusual presentation of chronic lymphocytic leukemia
publisher	Thieme Medical and Scientific Publishers Pvt. Ltd.
publishDate	2017
url	https://doaj.org/article/afe53fafc617425aa29efae42c663f21
work_keys_str_mv	AT dineshatwal anunusualpresentationofchroniclymphocyticleukemia AT mihirraval anunusualpresentationofchroniclymphocyticleukemia AT belalfirwana anunusualpresentationofchroniclymphocyticleukemia AT jeanetteramos anunusualpresentationofchroniclymphocyticleukemia AT appalanaidusasapu anunusualpresentationofchroniclymphocyticleukemia AT dineshatwal unusualpresentationofchroniclymphocyticleukemia AT mihirraval unusualpresentationofchroniclymphocyticleukemia AT belalfirwana unusualpresentationofchroniclymphocyticleukemia AT jeanetteramos unusualpresentationofchroniclymphocyticleukemia AT appalanaidusasapu unusualpresentationofchroniclymphocyticleukemia
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An unusual presentation of chronic lymphocytic leukemia

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