JunB promotes Th17 cell identity and restrains alternative CD4+ T-cell programs during inflammation

AP-1 family transcription factors regulate CD4+ T helper cell differentiation. Here the authors show that the AP-1 member JunB is a nonredundant regulator of transcriptional programs that support Th17 cell identity and restrain alternative Th1 and Treg cell fates in inflammatory contexts of acute fu...

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Autores principales:	Tiffany M. Carr, Joshua D. Wheaton, Geoffrey M. Houtz, Maria Ciofani
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2017
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/aff65dea708f44459ed50ef3c5241fa6
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spelling	oai:doaj.org-article:aff65dea708f44459ed50ef3c5241fa62021-12-02T10:48:28ZJunB promotes Th17 cell identity and restrains alternative CD4+ T-cell programs during inflammation10.1038/s41467-017-00380-32041-1723https://doaj.org/article/aff65dea708f44459ed50ef3c5241fa62017-08-01T00:00:00Zhttps://doi.org/10.1038/s41467-017-00380-3https://doaj.org/toc/2041-1723AP-1 family transcription factors regulate CD4+ T helper cell differentiation. Here the authors show that the AP-1 member JunB is a nonredundant regulator of transcriptional programs that support Th17 cell identity and restrain alternative Th1 and Treg cell fates in inflammatory contexts of acute fungal infection and chronic autoimmunity.Tiffany M. CarrJoshua D. WheatonGeoffrey M. HoutzMaria CiofaniNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-18 (2017)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Tiffany M. Carr Joshua D. Wheaton Geoffrey M. Houtz Maria Ciofani JunB promotes Th17 cell identity and restrains alternative CD4+ T-cell programs during inflammation
description	AP-1 family transcription factors regulate CD4+ T helper cell differentiation. Here the authors show that the AP-1 member JunB is a nonredundant regulator of transcriptional programs that support Th17 cell identity and restrain alternative Th1 and Treg cell fates in inflammatory contexts of acute fungal infection and chronic autoimmunity.
format	article
author	Tiffany M. Carr Joshua D. Wheaton Geoffrey M. Houtz Maria Ciofani
author_facet	Tiffany M. Carr Joshua D. Wheaton Geoffrey M. Houtz Maria Ciofani
author_sort	Tiffany M. Carr
title	JunB promotes Th17 cell identity and restrains alternative CD4+ T-cell programs during inflammation
title_short	JunB promotes Th17 cell identity and restrains alternative CD4+ T-cell programs during inflammation
title_full	JunB promotes Th17 cell identity and restrains alternative CD4+ T-cell programs during inflammation
title_fullStr	JunB promotes Th17 cell identity and restrains alternative CD4+ T-cell programs during inflammation
title_full_unstemmed	JunB promotes Th17 cell identity and restrains alternative CD4+ T-cell programs during inflammation
title_sort	junb promotes th17 cell identity and restrains alternative cd4+ t-cell programs during inflammation
publisher	Nature Portfolio
publishDate	2017
url	https://doaj.org/article/aff65dea708f44459ed50ef3c5241fa6
work_keys_str_mv	AT tiffanymcarr junbpromotesth17cellidentityandrestrainsalternativecd4tcellprogramsduringinflammation AT joshuadwheaton junbpromotesth17cellidentityandrestrainsalternativecd4tcellprogramsduringinflammation AT geoffreymhoutz junbpromotesth17cellidentityandrestrainsalternativecd4tcellprogramsduringinflammation AT mariaciofani junbpromotesth17cellidentityandrestrainsalternativecd4tcellprogramsduringinflammation
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JunB promotes Th17 cell identity and restrains alternative CD4+ T-cell programs during inflammation

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