Deep learning to predict the lab-of-origin of engineered DNA

The synthetic biology era has seen a rapidly growing number of engineered DNA sequences. Here, the authors develop a deep learning method to predict the lab-of-origin of a DNA sequence based on hidden design signatures.

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Detalles Bibliográficos
Autores principales: Alec A. K. Nielsen, Christopher A. Voigt
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2018
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Acceso en línea:https://doaj.org/article/aff74158519949ea8e1e1dec52978d20
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Descripción
Sumario:The synthetic biology era has seen a rapidly growing number of engineered DNA sequences. Here, the authors develop a deep learning method to predict the lab-of-origin of a DNA sequence based on hidden design signatures.