Deep learning to predict the lab-of-origin of engineered DNA

The synthetic biology era has seen a rapidly growing number of engineered DNA sequences. Here, the authors develop a deep learning method to predict the lab-of-origin of a DNA sequence based on hidden design signatures.

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Autores principales: Alec A. K. Nielsen, Christopher A. Voigt
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2018
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Acceso en línea:https://doaj.org/article/aff74158519949ea8e1e1dec52978d20
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spelling oai:doaj.org-article:aff74158519949ea8e1e1dec52978d202021-12-02T17:32:48ZDeep learning to predict the lab-of-origin of engineered DNA10.1038/s41467-018-05378-z2041-1723https://doaj.org/article/aff74158519949ea8e1e1dec52978d202018-08-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-05378-zhttps://doaj.org/toc/2041-1723The synthetic biology era has seen a rapidly growing number of engineered DNA sequences. Here, the authors develop a deep learning method to predict the lab-of-origin of a DNA sequence based on hidden design signatures.Alec A. K. NielsenChristopher A. VoigtNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-10 (2018)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Alec A. K. Nielsen
Christopher A. Voigt
Deep learning to predict the lab-of-origin of engineered DNA
description The synthetic biology era has seen a rapidly growing number of engineered DNA sequences. Here, the authors develop a deep learning method to predict the lab-of-origin of a DNA sequence based on hidden design signatures.
format article
author Alec A. K. Nielsen
Christopher A. Voigt
author_facet Alec A. K. Nielsen
Christopher A. Voigt
author_sort Alec A. K. Nielsen
title Deep learning to predict the lab-of-origin of engineered DNA
title_short Deep learning to predict the lab-of-origin of engineered DNA
title_full Deep learning to predict the lab-of-origin of engineered DNA
title_fullStr Deep learning to predict the lab-of-origin of engineered DNA
title_full_unstemmed Deep learning to predict the lab-of-origin of engineered DNA
title_sort deep learning to predict the lab-of-origin of engineered dna
publisher Nature Portfolio
publishDate 2018
url https://doaj.org/article/aff74158519949ea8e1e1dec52978d20
work_keys_str_mv AT alecaknielsen deeplearningtopredictthelaboforiginofengineereddna
AT christopheravoigt deeplearningtopredictthelaboforiginofengineereddna
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