Structural basis for late maturation steps of the human mitoribosomal large subunit

Structural basis for late maturation steps of the human mitoribosomal large subunit

Mitochondrial ribosomes (mitoribosomes) are characterized by a distinct architecture and thus biogenesis pathway. Here, cryo-EM structures of mitoribosome large subunit assembly intermediates elucidate final steps of 16 S rRNA folding, methylation and peptidyl transferase centre (PTC) completion, as...

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Autores principales: Miriam Cipullo, Genís Valentín Gesé, Anas Khawaja, B. Martin Hällberg, Joanna Rorbach
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Science
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Acceso en línea:https://doaj.org/article/afff746beaad42ec9209fdaff85ed8ec
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