A New Quaternary Structure Epitope on Dengue Virus Serotype 2 Is the Target of Durable Type-Specific Neutralizing Antibodies

A New Quaternary Structure Epitope on Dengue Virus Serotype 2 Is the Target of Durable Type-Specific Neutralizing Antibodies

ABSTRACT Dengue virus serotype 2 (DENV2) is widespread and responsible for severe epidemics. While primary DENV2 infections stimulate serotype-specific protective responses, a leading vaccine failed to induce a similar protective response. Using human monoclonal antibodies (hMAbs) isolated from deng...

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Bibliographic Details
Main Authors: E. N. Gallichotte, D. G. Widman, B. L. Yount, W. M. Wahala, A. Durbin, S. Whitehead, C. A. Sariol, J. E. Crowe, A. M. de Silva, R. S. Baric
Format: article
Language:EN
Published: American Society for Microbiology 2015
Subjects:
Microbiology
QR1-502
Online Access:https://doaj.org/article/b00e311a91e041c5b449557878544c2c
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https://doaj.org/article/b00e311a91e041c5b449557878544c2c

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