Discovery of novel therapeutic properties of drugs from transcriptional responses based on multi-label classification
Abstract Drug repositioning strategies have improved substantially in recent years. At present, two advances are poised to facilitate new strategies. First, the LINCS project can provide rich transcriptome data that reflect the responses of cells upon exposure to various drugs. Second, machine learn...
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Autores principales: | Lingwei Xie, Song He, Yuqi Wen, Xiaochen Bo, Zhongnan Zhang |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2017
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Materias: | |
Acceso en línea: | https://doaj.org/article/b013c36805df4c8d9dc018e1d5349f5c |
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