Discovery of novel therapeutic properties of drugs from transcriptional responses based on multi-label classification

Abstract Drug repositioning strategies have improved substantially in recent years. At present, two advances are poised to facilitate new strategies. First, the LINCS project can provide rich transcriptome data that reflect the responses of cells upon exposure to various drugs. Second, machine learn...

Full description

Saved in:
Bibliographic Details
Main Authors: Lingwei Xie, Song He, Yuqi Wen, Xiaochen Bo, Zhongnan Zhang
Format: article
Language:EN
Published: Nature Portfolio 2017
Subjects:
R
Q
Online Access:https://doaj.org/article/b013c36805df4c8d9dc018e1d5349f5c
Tags: Add Tag
No Tags, Be the first to tag this record!