Trabeculectomy versus Ahmed Glaucoma Valve implantation in neovascular glaucoma

Christopher C Shen1, Sarwat Salim2, Haiming Du2, Peter A Netland31Glaucoma Consultants Northwest, Seattle, WA, USA; 2University of Tennessee Health Science Center, Memphis, TN, USA; 3University of Virginia School of Medicine, Charlottesville, VA, USAPurpose: To compare surgical outcomes in neovascul...

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Autores principales: Christopher C Shen, Sarwat Salim, Haiming Du, et al
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Publicado: Dove Medical Press 2011
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spelling oai:doaj.org-article:b016786581b040c3a9256eb237a6e8672021-12-02T05:17:38ZTrabeculectomy versus Ahmed Glaucoma Valve implantation in neovascular glaucoma1177-54671177-5483https://doaj.org/article/b016786581b040c3a9256eb237a6e8672011-03-01T00:00:00Zhttp://www.dovepress.com/trabeculectomy-versus-ahmed-glaucoma-valve-implantation-in-neovascular-a6499https://doaj.org/toc/1177-5467https://doaj.org/toc/1177-5483Christopher C Shen1, Sarwat Salim2, Haiming Du2, Peter A Netland31Glaucoma Consultants Northwest, Seattle, WA, USA; 2University of Tennessee Health Science Center, Memphis, TN, USA; 3University of Virginia School of Medicine, Charlottesville, VA, USAPurpose: To compare surgical outcomes in neovascular glaucoma patients who underwent trabeculectomy with mitomycin C versus Ahmed Glaucoma Valve implantation. Patients and methods: This was a retrospective comparative case series. We reviewed 40 eyes of 39 patients with underlying diagnosis of neovascular glaucoma, divided into two groups: Ahmed Glaucoma Valve (N = 20) and trabeculectomy with mitomycin C (N = 20). Surgical success was defined as 6 mm Hg ≤ intraocular pressure ≤ 21 mm Hg, with or without the use of glaucoma medications, with no further glaucoma surgery, and light perception or better vision. Early postoperative hypotony was defined as intraocular pressure < 5 mm Hg during the first postoperative week.Results: The average follow-up was 31 months (range 6–87 months) for the Ahmed Glaucoma Valve group and 25 months (6–77 months) for the trabeculectomy group. Although the mean number of postoperative intraocular pressure-lowering medications was significantly higher in the trabeculectomy group compared with the Ahmed Glaucoma Valve group at 3 and 6 month time points, there was no statistically significant difference at any other time point. There was no statistically significant difference between both groups in postoperative visual acuity and intraocular pressure. Success was 70% and 65% at 1 year and 60% and 55% at 2 years after Ahmed Glaucoma Valve and trabeculectomy, respectively. Kaplan–Meier survival curve analysis showed no significant difference in success between the two groups (P = 0.815). Hyphema was the most common complication in both groups.Conclusion: We found similar results after trabeculectomy with mitomycin C and Ahmed Glaucoma Valve implantation in eyes with neovascular glaucoma.Keywords: glaucoma drainage implant, glaucoma filtering surgery, mitomycin C, neovascular glaucoma, intraocular pressure Christopher C ShenSarwat SalimHaiming Duet alDove Medical PressarticleOphthalmologyRE1-994ENClinical Ophthalmology, Vol 2011, Iss default, Pp 281-286 (2011)
institution DOAJ
collection DOAJ
language EN
topic Ophthalmology
RE1-994
spellingShingle Ophthalmology
RE1-994
Christopher C Shen
Sarwat Salim
Haiming Du
et al
Trabeculectomy versus Ahmed Glaucoma Valve implantation in neovascular glaucoma
description Christopher C Shen1, Sarwat Salim2, Haiming Du2, Peter A Netland31Glaucoma Consultants Northwest, Seattle, WA, USA; 2University of Tennessee Health Science Center, Memphis, TN, USA; 3University of Virginia School of Medicine, Charlottesville, VA, USAPurpose: To compare surgical outcomes in neovascular glaucoma patients who underwent trabeculectomy with mitomycin C versus Ahmed Glaucoma Valve implantation. Patients and methods: This was a retrospective comparative case series. We reviewed 40 eyes of 39 patients with underlying diagnosis of neovascular glaucoma, divided into two groups: Ahmed Glaucoma Valve (N = 20) and trabeculectomy with mitomycin C (N = 20). Surgical success was defined as 6 mm Hg ≤ intraocular pressure ≤ 21 mm Hg, with or without the use of glaucoma medications, with no further glaucoma surgery, and light perception or better vision. Early postoperative hypotony was defined as intraocular pressure < 5 mm Hg during the first postoperative week.Results: The average follow-up was 31 months (range 6–87 months) for the Ahmed Glaucoma Valve group and 25 months (6–77 months) for the trabeculectomy group. Although the mean number of postoperative intraocular pressure-lowering medications was significantly higher in the trabeculectomy group compared with the Ahmed Glaucoma Valve group at 3 and 6 month time points, there was no statistically significant difference at any other time point. There was no statistically significant difference between both groups in postoperative visual acuity and intraocular pressure. Success was 70% and 65% at 1 year and 60% and 55% at 2 years after Ahmed Glaucoma Valve and trabeculectomy, respectively. Kaplan–Meier survival curve analysis showed no significant difference in success between the two groups (P = 0.815). Hyphema was the most common complication in both groups.Conclusion: We found similar results after trabeculectomy with mitomycin C and Ahmed Glaucoma Valve implantation in eyes with neovascular glaucoma.Keywords: glaucoma drainage implant, glaucoma filtering surgery, mitomycin C, neovascular glaucoma, intraocular pressure
format article
author Christopher C Shen
Sarwat Salim
Haiming Du
et al
author_facet Christopher C Shen
Sarwat Salim
Haiming Du
et al
author_sort Christopher C Shen
title Trabeculectomy versus Ahmed Glaucoma Valve implantation in neovascular glaucoma
title_short Trabeculectomy versus Ahmed Glaucoma Valve implantation in neovascular glaucoma
title_full Trabeculectomy versus Ahmed Glaucoma Valve implantation in neovascular glaucoma
title_fullStr Trabeculectomy versus Ahmed Glaucoma Valve implantation in neovascular glaucoma
title_full_unstemmed Trabeculectomy versus Ahmed Glaucoma Valve implantation in neovascular glaucoma
title_sort trabeculectomy versus ahmed glaucoma valve implantation in neovascular glaucoma
publisher Dove Medical Press
publishDate 2011
url https://doaj.org/article/b016786581b040c3a9256eb237a6e867
work_keys_str_mv AT christophercshen trabeculectomyversusahmedglaucomavalveimplantationinneovascularglaucoma
AT sarwatsalim trabeculectomyversusahmedglaucomavalveimplantationinneovascularglaucoma
AT haimingdu trabeculectomyversusahmedglaucomavalveimplantationinneovascularglaucoma
AT etal trabeculectomyversusahmedglaucomavalveimplantationinneovascularglaucoma
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