YY1-binding sites provide central switch functions in the PARP-1 gene expression network.

YY1-binding sites provide central switch functions in the PARP-1 gene expression network.

Evidence is presented for the involvement of the interplay between transcription factor Yin Yang 1 (YY1) and poly(ADP-ribose) polymerase-1 (PARP-1) in the regulation of mouse PARP-1 gene (muPARP-1) promoter activity. We identified potential YY1 binding motifs (BM) at seven positions in the muPARP-1...

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Autores principales: Martina Doetsch, Angela Gluch, Goran Poznanović, Juergen Bode, Melita Vidaković
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2012
Materias:
Medicine
R
Science
Q
Acceso en línea:https://doaj.org/article/b01a463362f2489684330bdf098c904b
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