Protein arginine N-methyltransferase 5 in colorectal carcinoma: Insights into mechanisms of pathogenesis and therapeutic strategies
Protein arginine N-methyltransferase 5 (PRMT5) enzyme is one of the eight canonical PRMTs, classified as a type II PRMT, induces arginine monomethylation and symmetric dimethylation. PRMT5 is known to be overexpressed in multiple cancer types, including colorectal cancer (CRC), where its overexpress...
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Auteurs principaux: | Wafaa Abumustafa, Batoul Abi Zamer, Bariaa A. Khalil, Mawieh Hamad, Azzam A. Maghazachi, Jibran Sualeh Muhammad |
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Format: | article |
Langue: | EN |
Publié: |
Elsevier
2022
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Accès en ligne: | https://doaj.org/article/b01cd0d624564e58b94a9ab843e7ab63 |
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