Protein arginine N-methyltransferase 5 in colorectal carcinoma: Insights into mechanisms of pathogenesis and therapeutic strategies

Protein arginine N-methyltransferase 5 in colorectal carcinoma: Insights into mechanisms of pathogenesis and therapeutic strategies

Protein arginine N-methyltransferase 5 (PRMT5) enzyme is one of the eight canonical PRMTs, classified as a type II PRMT, induces arginine monomethylation and symmetric dimethylation. PRMT5 is known to be overexpressed in multiple cancer types, including colorectal cancer (CRC), where its overexpress...

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Autores principales: Wafaa Abumustafa, Batoul Abi Zamer, Bariaa A. Khalil, Mawieh Hamad, Azzam A. Maghazachi, Jibran Sualeh Muhammad
Formato: article
Lenguaje:EN
Publicado: Elsevier 2022
Materias:
PRMT5
Colorectal cancer
Epigenetics
Histone modification
Theranostics
Therapeutics. Pharmacology
RM1-950
Acceso en línea:https://doaj.org/article/b01cd0d624564e58b94a9ab843e7ab63
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https://doaj.org/article/b01cd0d624564e58b94a9ab843e7ab63

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