MicroRNA-224 targets SMAD family member 4 to promote cell proliferation and negatively influence patient survival.

MicroRNA-224 (miR-224) is frequently over-expressed in liver and colorectal cancers. We and others have previously described the role of miR-224 over-expression in cell proliferation in vitro but we have yet to identify the relevant miR-224 direct target. In this study, we further demonstrated that...

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Autores principales: Yu Wang, Jianwei Ren, Yun Gao, Joel Z I Ma, Han Chong Toh, Pierce Chow, Alexander Y F Chung, London L P J Ooi, Caroline G L Lee
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2013
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Acceso en línea:https://doaj.org/article/b02347caf191495fa33d49eaff6e98a5
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