The nuclear pore primes recombination-dependent DNA synthesis at arrested forks by promoting SUMO removal
In yeast, collapsed forks shift to the nuclear periphery to associate with two distinct perinuclear anchorage sites such as the nuclear pore complex. Here, the authors reveal the mechanisms engaged at nuclear pore complex facilitating fork integrity and restart via SUMO regulation.
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2020
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oai:doaj.org-article:b024f89b69c54014a61545e22ef456042021-12-02T15:37:18ZThe nuclear pore primes recombination-dependent DNA synthesis at arrested forks by promoting SUMO removal10.1038/s41467-020-19516-z2041-1723https://doaj.org/article/b024f89b69c54014a61545e22ef456042020-11-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-19516-zhttps://doaj.org/toc/2041-1723In yeast, collapsed forks shift to the nuclear periphery to associate with two distinct perinuclear anchorage sites such as the nuclear pore complex. Here, the authors reveal the mechanisms engaged at nuclear pore complex facilitating fork integrity and restart via SUMO regulation.Karol KramarzKamila SchirmeisenVirginie BoucheritAnissia Ait SaadaClaire LovoBenoit PalancadeCatherine FreudenreichSarah A. E. LambertNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-15 (2020) |
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Science Q Karol Kramarz Kamila Schirmeisen Virginie Boucherit Anissia Ait Saada Claire Lovo Benoit Palancade Catherine Freudenreich Sarah A. E. Lambert The nuclear pore primes recombination-dependent DNA synthesis at arrested forks by promoting SUMO removal |
description |
In yeast, collapsed forks shift to the nuclear periphery to associate with two distinct perinuclear anchorage sites such as the nuclear pore complex. Here, the authors reveal the mechanisms engaged at nuclear pore complex facilitating fork integrity and restart via SUMO regulation. |
format |
article |
author |
Karol Kramarz Kamila Schirmeisen Virginie Boucherit Anissia Ait Saada Claire Lovo Benoit Palancade Catherine Freudenreich Sarah A. E. Lambert |
author_facet |
Karol Kramarz Kamila Schirmeisen Virginie Boucherit Anissia Ait Saada Claire Lovo Benoit Palancade Catherine Freudenreich Sarah A. E. Lambert |
author_sort |
Karol Kramarz |
title |
The nuclear pore primes recombination-dependent DNA synthesis at arrested forks by promoting SUMO removal |
title_short |
The nuclear pore primes recombination-dependent DNA synthesis at arrested forks by promoting SUMO removal |
title_full |
The nuclear pore primes recombination-dependent DNA synthesis at arrested forks by promoting SUMO removal |
title_fullStr |
The nuclear pore primes recombination-dependent DNA synthesis at arrested forks by promoting SUMO removal |
title_full_unstemmed |
The nuclear pore primes recombination-dependent DNA synthesis at arrested forks by promoting SUMO removal |
title_sort |
nuclear pore primes recombination-dependent dna synthesis at arrested forks by promoting sumo removal |
publisher |
Nature Portfolio |
publishDate |
2020 |
url |
https://doaj.org/article/b024f89b69c54014a61545e22ef45604 |
work_keys_str_mv |
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