Hybrid mass spectrometry approaches in glycoprotein analysis and their usage in scoring biosimilarity
Many biopharmaceuticals exhibit mixed heterogeneity in their post-translational modifications (PTMs) that are essential for their function. Here the authors use a combination of mass spectrometry techniques to analyse human erythropoietin (EPO) and properdin to discover new PTMs on properdin and der...
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Auteurs principaux: | Yang Yang, Fan Liu, Vojtech Franc, Liem Andhyk Halim, Huub Schellekens, Albert J. R. Heck |
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Format: | article |
Langue: | EN |
Publié: |
Nature Portfolio
2016
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Accès en ligne: | https://doaj.org/article/b02ee70614ff4f99a5c217410f8e376c |
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