Interplay of active processes modulates tension and drives phase transition in self-renewing, motor-driven cytoskeletal networks
The actin cytoskeleton is a complex network of filaments, cross-linking proteins and motors; although the components are recognised, the behaviour of the network is less understood. Here Mak et al.use a Brownian dynamics model that reveals actin turnover dynamics as a key regulatory mechanism contro...
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2016
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oai:doaj.org-article:b03a6e4804b340c98616e8218780f4942021-12-02T14:39:54ZInterplay of active processes modulates tension and drives phase transition in self-renewing, motor-driven cytoskeletal networks10.1038/ncomms103232041-1723https://doaj.org/article/b03a6e4804b340c98616e8218780f4942016-01-01T00:00:00Zhttps://doi.org/10.1038/ncomms10323https://doaj.org/toc/2041-1723The actin cytoskeleton is a complex network of filaments, cross-linking proteins and motors; although the components are recognised, the behaviour of the network is less understood. Here Mak et al.use a Brownian dynamics model that reveals actin turnover dynamics as a key regulatory mechanism controlling cytoskeletal states.Michael MakMuhammad H. ZamanRoger D. KammTaeyoon KimNature PortfolioarticleScienceQENNature Communications, Vol 7, Iss 1, Pp 1-12 (2016) |
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Science Q Michael Mak Muhammad H. Zaman Roger D. Kamm Taeyoon Kim Interplay of active processes modulates tension and drives phase transition in self-renewing, motor-driven cytoskeletal networks |
description |
The actin cytoskeleton is a complex network of filaments, cross-linking proteins and motors; although the components are recognised, the behaviour of the network is less understood. Here Mak et al.use a Brownian dynamics model that reveals actin turnover dynamics as a key regulatory mechanism controlling cytoskeletal states. |
format |
article |
author |
Michael Mak Muhammad H. Zaman Roger D. Kamm Taeyoon Kim |
author_facet |
Michael Mak Muhammad H. Zaman Roger D. Kamm Taeyoon Kim |
author_sort |
Michael Mak |
title |
Interplay of active processes modulates tension and drives phase transition in self-renewing, motor-driven cytoskeletal networks |
title_short |
Interplay of active processes modulates tension and drives phase transition in self-renewing, motor-driven cytoskeletal networks |
title_full |
Interplay of active processes modulates tension and drives phase transition in self-renewing, motor-driven cytoskeletal networks |
title_fullStr |
Interplay of active processes modulates tension and drives phase transition in self-renewing, motor-driven cytoskeletal networks |
title_full_unstemmed |
Interplay of active processes modulates tension and drives phase transition in self-renewing, motor-driven cytoskeletal networks |
title_sort |
interplay of active processes modulates tension and drives phase transition in self-renewing, motor-driven cytoskeletal networks |
publisher |
Nature Portfolio |
publishDate |
2016 |
url |
https://doaj.org/article/b03a6e4804b340c98616e8218780f494 |
work_keys_str_mv |
AT michaelmak interplayofactiveprocessesmodulatestensionanddrivesphasetransitioninselfrenewingmotordrivencytoskeletalnetworks AT muhammadhzaman interplayofactiveprocessesmodulatestensionanddrivesphasetransitioninselfrenewingmotordrivencytoskeletalnetworks AT rogerdkamm interplayofactiveprocessesmodulatestensionanddrivesphasetransitioninselfrenewingmotordrivencytoskeletalnetworks AT taeyoonkim interplayofactiveprocessesmodulatestensionanddrivesphasetransitioninselfrenewingmotordrivencytoskeletalnetworks |
_version_ |
1718390493800300544 |