Architecture of a mammalian glomerular domain revealed by novel volume electroporation using nanoengineered microelectrodes

Microcircuit tracing reconstructions often rely on statistical labeling that may not detect all inputs and outputs of a microcircuit. Here the authors employ a novel electroporation approach to densely label neurons and demonstrate its ability to identify sparse anatomical features in the olfactory...

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Autores principales: D. Schwarz, M. Kollo, C. Bosch, C. Feinauer, I. Whiteley, T. W. Margrie, T. Cutforth, A. T. Schaefer
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2018
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Acceso en línea:https://doaj.org/article/b03e88f02f8742de9a8604673e0f0a5e
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Sumario:Microcircuit tracing reconstructions often rely on statistical labeling that may not detect all inputs and outputs of a microcircuit. Here the authors employ a novel electroporation approach to densely label neurons and demonstrate its ability to identify sparse anatomical features in the olfactory glomerulus.