Analysis of a Tuberculosis Infection Model considering the Influence of Saturated Recovery (Treatment)

Tuberculosis (TB) is a serious global health threat that is caused by the bacterium Mycobacterium tuberculosis, is extremely infectious, and has a high mortality rate. In this paper, we developed a model of TB infection to predict the impact of saturated recovery. The existence of equilibrium and it...

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Autores principales: Fatima Sulayman, Farah Aini Abdullah
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Lenguaje:EN
Publicado: Hindawi-Wiley 2021
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Acceso en línea:https://doaj.org/article/b04091ea7ba2482793f138a47cf3af03
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spelling oai:doaj.org-article:b04091ea7ba2482793f138a47cf3af032021-11-22T01:09:44ZAnalysis of a Tuberculosis Infection Model considering the Influence of Saturated Recovery (Treatment)1099-052610.1155/2021/1805651https://doaj.org/article/b04091ea7ba2482793f138a47cf3af032021-01-01T00:00:00Zhttp://dx.doi.org/10.1155/2021/1805651https://doaj.org/toc/1099-0526Tuberculosis (TB) is a serious global health threat that is caused by the bacterium Mycobacterium tuberculosis, is extremely infectious, and has a high mortality rate. In this paper, we developed a model of TB infection to predict the impact of saturated recovery. The existence of equilibrium and its stability has been investigated based on the effective reproduction number RC. The model displays interesting dynamics, including backward bifurcation and Hopf bifurcation, which further results in the stable disease-free and stable endemic equilibria to be coexisting. Bifurcation analysis demonstrates that the saturation parameter is accountable for the phenomenon of backward bifurcation. We derive a condition that guarantees that the model is globally asymptotically stable using the Lyapunov function approach to global stability. The numerical simulation also reveals that the extent of saturation of TB infection is the mechanism that is fuelling TB disease in the population.Fatima SulaymanFarah Aini AbdullahHindawi-WileyarticleElectronic computers. Computer scienceQA75.5-76.95ENComplexity, Vol 2021 (2021)
institution DOAJ
collection DOAJ
language EN
topic Electronic computers. Computer science
QA75.5-76.95
spellingShingle Electronic computers. Computer science
QA75.5-76.95
Fatima Sulayman
Farah Aini Abdullah
Analysis of a Tuberculosis Infection Model considering the Influence of Saturated Recovery (Treatment)
description Tuberculosis (TB) is a serious global health threat that is caused by the bacterium Mycobacterium tuberculosis, is extremely infectious, and has a high mortality rate. In this paper, we developed a model of TB infection to predict the impact of saturated recovery. The existence of equilibrium and its stability has been investigated based on the effective reproduction number RC. The model displays interesting dynamics, including backward bifurcation and Hopf bifurcation, which further results in the stable disease-free and stable endemic equilibria to be coexisting. Bifurcation analysis demonstrates that the saturation parameter is accountable for the phenomenon of backward bifurcation. We derive a condition that guarantees that the model is globally asymptotically stable using the Lyapunov function approach to global stability. The numerical simulation also reveals that the extent of saturation of TB infection is the mechanism that is fuelling TB disease in the population.
format article
author Fatima Sulayman
Farah Aini Abdullah
author_facet Fatima Sulayman
Farah Aini Abdullah
author_sort Fatima Sulayman
title Analysis of a Tuberculosis Infection Model considering the Influence of Saturated Recovery (Treatment)
title_short Analysis of a Tuberculosis Infection Model considering the Influence of Saturated Recovery (Treatment)
title_full Analysis of a Tuberculosis Infection Model considering the Influence of Saturated Recovery (Treatment)
title_fullStr Analysis of a Tuberculosis Infection Model considering the Influence of Saturated Recovery (Treatment)
title_full_unstemmed Analysis of a Tuberculosis Infection Model considering the Influence of Saturated Recovery (Treatment)
title_sort analysis of a tuberculosis infection model considering the influence of saturated recovery (treatment)
publisher Hindawi-Wiley
publishDate 2021
url https://doaj.org/article/b04091ea7ba2482793f138a47cf3af03
work_keys_str_mv AT fatimasulayman analysisofatuberculosisinfectionmodelconsideringtheinfluenceofsaturatedrecoverytreatment
AT farahainiabdullah analysisofatuberculosisinfectionmodelconsideringtheinfluenceofsaturatedrecoverytreatment
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