GWAS for urinary sodium and potassium excretion highlights pathways shared with cardiovascular traits

Levels of sodium and potassium in urine are associated with cardiovascular traits. Here, Pazoki et al. perform genome-wide association studies for urinary sodium and potassium secretion and identify 50 and 13 novel loci, respectively, some of which show a potential causal relationship with blood pre...

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Autores principales:	Raha Pazoki, Evangelos Evangelou, David Mosen-Ansorena, Rui Climaco Pinto, Ibrahim Karaman, Paul Blakeley, Dipender Gill, Verena Zuber, Paul Elliott, Ioanna Tzoulaki, Abbas Dehghan
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2019
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/b0491cd806ba41cd9e56d38859fd1475
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spelling	oai:doaj.org-article:b0491cd806ba41cd9e56d38859fd14752021-12-02T14:38:41ZGWAS for urinary sodium and potassium excretion highlights pathways shared with cardiovascular traits10.1038/s41467-019-11451-y2041-1723https://doaj.org/article/b0491cd806ba41cd9e56d38859fd14752019-08-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-11451-yhttps://doaj.org/toc/2041-1723Levels of sodium and potassium in urine are associated with cardiovascular traits. Here, Pazoki et al. perform genome-wide association studies for urinary sodium and potassium secretion and identify 50 and 13 novel loci, respectively, some of which show a potential causal relationship with blood pressure based on MR analysis.Raha PazokiEvangelos EvangelouDavid Mosen-AnsorenaRui Climaco PintoIbrahim KaramanPaul BlakeleyDipender GillVerena ZuberPaul ElliottIoanna TzoulakiAbbas DehghanNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-11 (2019)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Raha Pazoki Evangelos Evangelou David Mosen-Ansorena Rui Climaco Pinto Ibrahim Karaman Paul Blakeley Dipender Gill Verena Zuber Paul Elliott Ioanna Tzoulaki Abbas Dehghan GWAS for urinary sodium and potassium excretion highlights pathways shared with cardiovascular traits
description	Levels of sodium and potassium in urine are associated with cardiovascular traits. Here, Pazoki et al. perform genome-wide association studies for urinary sodium and potassium secretion and identify 50 and 13 novel loci, respectively, some of which show a potential causal relationship with blood pressure based on MR analysis.
format	article
author	Raha Pazoki Evangelos Evangelou David Mosen-Ansorena Rui Climaco Pinto Ibrahim Karaman Paul Blakeley Dipender Gill Verena Zuber Paul Elliott Ioanna Tzoulaki Abbas Dehghan
author_facet	Raha Pazoki Evangelos Evangelou David Mosen-Ansorena Rui Climaco Pinto Ibrahim Karaman Paul Blakeley Dipender Gill Verena Zuber Paul Elliott Ioanna Tzoulaki Abbas Dehghan
author_sort	Raha Pazoki
title	GWAS for urinary sodium and potassium excretion highlights pathways shared with cardiovascular traits
title_short	GWAS for urinary sodium and potassium excretion highlights pathways shared with cardiovascular traits
title_full	GWAS for urinary sodium and potassium excretion highlights pathways shared with cardiovascular traits
title_fullStr	GWAS for urinary sodium and potassium excretion highlights pathways shared with cardiovascular traits
title_full_unstemmed	GWAS for urinary sodium and potassium excretion highlights pathways shared with cardiovascular traits
title_sort	gwas for urinary sodium and potassium excretion highlights pathways shared with cardiovascular traits
publisher	Nature Portfolio
publishDate	2019
url	https://doaj.org/article/b0491cd806ba41cd9e56d38859fd1475
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GWAS for urinary sodium and potassium excretion highlights pathways shared with cardiovascular traits

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