Targeting TBK1 Attenuates LPS-Induced NLRP3 Inflammasome Activation by Regulating of mTORC1 Pathways in Trophoblasts
Pathological maternal inflammation and abnormal placentation contribute to several pregnancy-related disorders, including preterm birth, intrauterine growth restriction, and preeclampsia. TANK-binding kinase 1 (TBK1), a serine/threonine kinase, has been implicated in the regulation of various physio...
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Main Authors: | , , , , , |
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Format: | article |
Language: | EN |
Published: |
Frontiers Media S.A.
2021
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Subjects: | |
Online Access: | https://doaj.org/article/b05804b2a6a74dd6a1c36fa320f25701 |
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