A family of helminth molecules that modulate innate cell responses via molecular mimicry of host antimicrobial peptides.

Over the last decade a significant number of studies have highlighted the central role of host antimicrobial (or defence) peptides in modulating the response of innate immune cells to pathogen-associated ligands. In humans, the most widely studied antimicrobial peptide is LL-37, a 37-residue peptide...

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Auteurs principaux: Mark W Robinson, Sheila Donnelly, Andrew T Hutchinson, Joyce To, Nicole L Taylor, Raymond S Norton, Matthew A Perugini, John P Dalton
Format: article
Langue:EN
Publié: Public Library of Science (PLoS) 2011
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Accès en ligne:https://doaj.org/article/b058d9f038fc40e09234c67174aa24b4
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